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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 13, Issue:6, June, 2024

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2024.13(6): 69-77
DOI: https://doi.org/10.20546/ijcmas.2024.1306.007


Incidence of Mucormycosis, An Invasive Fungal Infection and its Relation with Covid-19 in A Tertiary Care Centre in Jammu
Perika1, Priyanka Sharma2*, Suharshi Gupta3, Sikander Chairag4, Shashi Sudhan Sharma5 and Mukesh Kumar6
1Medical Officer, Department of Microbiology, GMC Jammu
2Lecturer, Medical Officer, Department of Microbiology, GMC Jammu
3Medical Officer, Co-PI, VRDL, Department of Microbiology, GMC Jammu
4Assistant Professor, Department of Microbiology, GMC Jammu
5Prof. and Head, PI. & Nodal Officer, VRDL, Department of Microbiology, GMC Jammu
6Lab.Technician, Department of Microbiology, GMC Jammu
*Corresponding author
Abstract:

Mucormycosis, an invasive fungal infection has been seen to affect a large number of COVID-19 patients due to the overdosage, panic and injudicious use of corticosteroids among COVID-19 patients and presence of diabetes as a risk factor increases the chances of getting COVID-19 infection. The combination of Mucormycosis and COVID-19 infection has posed a double health threat to a collapsing healthcare system in India. Hence, the present study was conducted to study the incidence of Mucormycosis and its relation with COVID-19 so that awareness among the public can be generated and appropriate steps could be planned to combat the syndemic of COVID-19 and Mucormycosis. In our study, a total of 30 cases of Mucormycosis were reported, out of which Rhinocerebral Mucormycosis (RCOM) was the most common type 25(83.3%). Among the cases, 20 (66.6%) were male and 10 (33.33 %) were female. Maximum cases- 15 (45.8%) were in 51-60 years age group and among the cases, 18 (75%) were COVID positive. The present study was planned so that early diagnosis of such cases could be done, which would further help in providing appropriate treatment and hence subsequent reduction of morbidity and mortality.


Keywords: COVID-19, Mucormycosis, Immuocompromised, Invasive Fungal Infection


References:

Bala K, Chander J, Handa U, Punia R S, Attri A K. A prospective study of mucormycosis in north India: Experience from a tertiary care hospital. Int Soc Hum Anim Myc. 2015; 53(3): 248-257. https://doi.org/10.1093/mmy/myu086

Bhat I, Beg M A, Athar F. A contemporary intimidation for COVID-19 patients coinfected with mucormycosis in India. J Bacteriol Mycol Open Access 2021; 9(2):69-71. https://doi.org/10.15406/jbmoa.2021.09.00298

Chakrabarti A, Chatterjee S S, Das A et al., Invasive zygomycosis in India: experience in a tertiary care hospital. Postgrad Med J 2009; 85: 573–81. https://doi.org/10.1136/pgmj.2008.076463

Chakrabarti A, Das A, Mandal J et al., The rising trend of invasive zygomycosis in patients with uncontrolled diabetes mellitus. Med Mycol 2006; 44: 335–42. https://doi.org/10.1080/13693780500464930

Chakrabarti A, Das A, Sharma A et al., Ten years’ experience in Zygomycosis at a tertiary care centre in India. J Infect 2001; 42: 261–6. https://doi.org/10.1053/jinf.2001.0831

Chakrabarti A, Singh R. The emerging epidemiology of mould infections in developing countries. Curr Opin Infect Dis 2011; 24: 521–6. https://doi.org/10.1097/QCO.0b013e32834ab21e

India: WHO Coronavirus Disease (COVID-19) Dashboard With Vaccination Data | WHO Coronavirus (COVID-19) Dashboard With Vaccination Data. (Available from: https://covid19.who.int/region/searo/country/in) [9 Jun 2021]

Kontoyiannis D P, Yang H, Song J et al., Prevalence, clinical and economic burden of mucormycosis-related hospitalizations in the United States: a retrospective study. BMC Infect Dis. 2016; 16: 730. https://doi.org/10.1186/s12879-016-2023-z

Mantadakis E, Samonis G. Clinical presentation of zygomycosis. Clin Microbiol Infect 2009; 15(Suppl. 5): 15–20. https://doi.org/10.1111/j.1469-0691.2009.02974.x

Meis J F, Chakrabarti A. Changing epidemiology of an emerging Infection: zygomycosis. Clin Microbiol Infect 2009; 15(Suppl. 5): 10– 4. https://doi.org/10.1111/j.1469-0691.2009.02973.x

Over 28,200 “black fungus” cases recorded In India. (Available from: https://www.aa.com.tr/en/asia-pacific/over-28-200-black-fungus-cases-recorded-in-india/2266396) [9 Jun 2021]

Patel A, Kaur H, Xess I, Michael J S, Savio J, Rudramurthy S et al., A multicentre observational study on the epidemiology, risk factors, management and outcomes of mucormycosis in India. Clin. Microbiol. Infect. https://doi.org/10.1016/j.cmi.2019.11.021

Prakash H, Ghosh A K, Rudramurthy S M, Singh P, Xess I, Savio J et al., A prospective multicenter study on mucormycosis in India: Epidemiology, diagnosis, and treatment. Med Mycol. 2019 Jun 1; 57(4):395-402. https://doi.org/10.1093/mmy/myy060

Ribes J A, Vanover-Sams C L, Baker D J. Zygomycetes in human disease. Clin Microbiol Rev 2002; 13: 236–301. https://doi.org/10.1128/CMR.13.2.236

Skiada A, Pagano L, Groll A et al., Zygomycosis in Europe: analysis of 230 cases accrued by the registry of the European Confederation of Medical Mycology (ECMM) Working Group on Zygomycosis between 2005 and 2007. Clin Microbio Infect. 2011; 17: 1859–1867. https://doi.org/10.1111/j.1469-0691.2010.03456.x


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How to cite this article:

Perika, Priyanka Sharma, Suharshi Gupta, Sikander Chairag, Shashi Sudhan Sharma and Mukesh Kumar. 2024. Incidence of Mucormycosis, An Invasive Fungal Infection and its Relation with Covid-19 in A Tertiary Care Centre in Jammu.Int.J.Curr.Microbiol.App.Sci. 13(6): 69-77. doi: https://doi.org/10.20546/ijcmas.2024.1306.007
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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