National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Bacterial strains causing extra intestinal infections harbor virulence factors that enhance the ability to cause systemic infection. Uropathogenic Escherichia coli (UPEC) responsible for UTI express a multitude of virulence factors to break the inertia of the mucosal barrier. To study the haemolysin, haemagglutination and resistance to the bactericidal activity of the serum property as urovirulence factors of E.coli and antimicrobial susceptibility pattern. 100 E.coli strains isolated from urine samples out of 400 symptomatic cases were screened for virulence factors like Haemolysin, Mannose resistant, Mannose sensitive Haemagglutination (MRHA, MSHA) and Serum resistance by phenotypic methods. Antimicrobial susceptibility testing was done by Kirby-Bauer disc diffusion method as per CLSI guidelines. Among 100 E.coli strains 33% were hemolytic, 9% showed MRHA, 14% showed MSHA, there was no haemagglutination in 73% strains and 76%were serum resistant. Least percentage of resistance was seen to Imipenem (1%), Piperacillin/tazobactum (1%) and Nitrofurantoin (19%). High percentage of resistance was found to Penicillins and Norfloxacin (79%). The present study revealed that UPEC exhibited one or more virulence factors. Identifying virulence markers will definitely prevent the complications like recurrent, chronic and persistent urinary tract infections.
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