Hepatitis is an inflammation of the liver, most commonly caused by a viral infection. In recent years India and other transitional economies are showing a significant epidemiological shift of HAV infection from high endemicity to intermediate endemicity. Approximately 240 million people are chronically infected with HBV worldwide, while 150 million people are infected with HCV There is a need for study of these etiological agents in jaundice for appropriate management as well as prevention of viral hepatitis. The aim of the present study was to evaluate seroprevalence of viral hepatitis A, B and C and E in patients presenting with viral Hepatitis. The study population comprised of 9263 patients presenting with acute hepatitis. Samples were collected from patients with clinically suspected acute infectious hepatitis at Hospital. Serum samples were collected Seroprevalence rate was calculated and stratified by age. Out of the 9263 adults with acute viral hepatitis studied, HAV was found to be the most common etiological agent (12.3%), followed by HEV (4.97%), HBV (3.54%) and HCV (2.08%). Co‑infections with more than one virus were present in 7 cases; HBV‑HCV co‑infection being the most common.

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