International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 5, Issue:9, September, 2016

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(9): 14-18

Seroprevalence of Rickettsial Diseases in a Tertiary Care Hospital
Mita D. Wadekar1* and N.B. Swaroop Rani2
1Assistant Professor
2Associate Professor, Department of Microbiology,
Subbaiah Institute of Medical Sciences, Shimoga, Karnataka, India  
*Corresponding author

Rickettsial diseases are still prevalent in most of the countries including India and are also classified under the causes of pyrexia of unknown origin (PUO). Early signs and symptoms of these infections are nonspecific making diagnosis more difficult. If untreated mortality may be as high as 30-35% . Though Weil Felix test is less sensitive but still it serves as a useful and cheapest available screening tool for the laboratory diagnosis of rickettsial diseases. A prospective study was carried out for a period of 6 months from November 2015 to April 2016 in a tertiary-care hospital, Shimoga, Karnataka, India. The serum samples from 277 PUO cases which included patients of all age group and from both Out Patient Department (OPD) and In Patient Department (IPD), were subjected to Weil–Felix test (PROGEN, Tulip Diagnostics (P) Ltd., Verna, Goa, India). The test was performed according to the manufacturer’s instructions. Serum samples positive in the slide test were confirmed with the tube test. Titers of more than 1:160 for OX-K and more than 1:80 for OX-2 and OX-19 were considered significant. Of 277 samples, rickettsial diseases were detected in 73(26.35%) samples. Seropositivity was higher among male subjects 52(71.23%) when compared with female subjects 21(28.77%). All positive cases were in 1-18 age group. Prevalence of rickettsial diseases 73(26.35%) is significantly high, especially in children’s and hence should be included in the differential diagnosis of PUO.

Keywords: Rickettsial diseases,PUO,Weil–Felix test.

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How to cite this article:

Mita D. Wadekar and N.B. Swaroop Rani. 2016. Seroprevalence of Rickettsial Diseases in a Tertiary Care Hospital.Int.J.Curr.Microbiol.App.Sci. 5(9): 14-18. doi:
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.