National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Hepatitis C virus (HCV) infection is a leading cause of chronic hepatitis and primary hepatocellular carcinoma in most parts of the world. The prevalence of HCV infection worldwide has been estimated to be about 3%. Hence the present study was carried out to detect the prevalence of hepatitis C in patients of chronic liver disease. Eighty patients with clinically suspected Chronic Liver Disease attending the outpatient department or admitted in the K R Hospital attached to Mysore Medical College and Research Institute, Mysore from January 2012 to December 2012, were screened for anti-HCV. The study also included 15 asymptomatic healthy individuals who constituted the control group. 5 ml of blood was collected from all patients with aseptic precautions, serum sample obtained were tested for serological marker anti-HCV using Erba Lisa Hepatitis C - third generation ELISA kits. Serum samples from healthy individuals included were also simultaneously screened for anti-HCV. Among the 80 chronic liver disease patients, 4(5%) were positive for HCV. Among the 4 HCV positive patients, all were males. The highest percentage of HCV positivity was in the age group 31 – 40 years. The main mode of transmission in HCV was through sexual exposure, 3 (75%). Among the 4 HCV positive patients, 3 (75%) presented with cirrhosis of liver and 1 (25%) with hepatocellular carcinoma. Among the healthy controls screened all were negative for anti HCV.
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