A combination of different antibiotics was mostly used in H pylori eradication. Eradication of H. pylori likely has a beneficial effect in preventing the development of subsequent gastric dysplasia,a premalignant lesion of gastric Ulcer. This study comprised fifty gastritis peptic ulcers patients, 24 of them were males and 26 were females. These patients were attending the gastroscope clinic at Gastroenterology center (GEC), Mansoura University Hospitals (MUHs), over 6 months, during the period from May 2015 to April 2016, with symptoms and signs suggesting gastritis. H pylori response to both Clarithromycin and Metronidazole antibiotic sensitivity was giving the same figures. In respect to gender, 90.9% of males and 88.2% of females were sensitive to both antibiotics. Tetracycline antibiotic sensitivity was showing that 81.8% of the males and 88.2% of the females were sensitive to Tetracycline antibiotics. H pylori response to both Clarithromycin and Metronidazole antibiotic sensitivity was giving the same figures. In respect to gender, 90.9% of males and 88.2% of females were sensitive to both antibiotics. Tetracycline antibiotic sensitivity was showing that 81.8% of the males and 88.2% of the females were sensitive to Tetracycline antibiotics.

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