The present study was planned to evaluate the effect of supplementing non-enzymatic antioxidants as adjunct therapy in enhancing clinical recovery of cattle naturally infected with bovine tropical theileriosis. A total of 18 crossbred dairy cattle with the clinical signs consistent of bovine tropical theileriosis and confirmation by detection of piroplasm infected erythrocytes in blood smears, were randomly divided into 3 groups (A, B, C) of 6 animals each. Animals in group A were treated with specific therapy, buparvaquone @ 2.5 mg/kg intramuscular once; group B treated with vitamin C @ 15 mg/kg intramuscular for nine days along with specific therapy and group C treated with vitamin E @ 1.5 mg/kg plus selenium @ 0.05 mg/kg intramuscular in three doses at three days interval along with specific therapy. The therapeutic evaluation was done on day 0, 3, 6 and 9 of therapy based upon alteration in haemato-biochemical profile and oxidative stress indices. Administration of buparvaquone alone led to disappearance of clinical signs; however, antioxidant supplementation adjunct to specific therapy hastened the clinical recovery. Quicker revival in haemato-biochemical profile was observed in animals of group C which were supplemented with vitamin E-selenium as compared to animals of group B. The oxidative stress indices in blood showed significant improvement in animals which were supplemented with antioxidants; however, more improvement was observed in animals of group C as compare to animals of group B. Thus, the present findings suggest vitamin E-selenium as better adjunct antioxidant therapy than vitamin C in bovine tropical theileriosis.

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