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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 6, Issue:11, November, 2017

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(11): 2861-2870
DOI: https://doi.org/10.20546/ijcmas.2017.611.337


Antimicrobial Activity of a Novel Secondary Metabolite from Streptomyces sp. and Molecular Docking Studies against Bacterial Leaf Blight Pathogen of Rice
Nanjundan Jaivel1*, Ramasamy Rajesh1, Devadasan Velmurugan2 and Ponnusamy Marimuthu1
1Department of Agricultural Microbiology, Tamil Nadu Agricultural University,Coimbatore, 641 003, Tamil Nadu, India
2Department of Crystallography and Biophysics, University of Madras,Chennai, 600 025, Tamil Nadu, India
*Corresponding author
Abstract:

The metabolite 2-(1,1-diallyl-but-3-enyl)-5-nonyl-phenol isolated from Streptomyces sp. TC1 exhibited antimicrobial activity against bacterial leaf blight pathogen Xanthomonas oryzae pv. oryzae (Xoo). The in vitro antimicrobial activity was found to be between 1.8-2.5 cm in agar well diffusion assay against the tested Xoo isolates and 200 µg/ml in terms of minimum inhibitory concentration. The isolated compound showed well binding with the virulence proteins of Xoo by producing a better docking score in molecular docking studies.


Keywords: Streptomyces sp., Antimicrobial, Xoo, MIC, Docking, 2-(1,1-diallyl-but-3-enyl)-5-nonyl-phenol.

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How to cite this article:

Nanjundan Jaivel, Ramasamy Rajesh, Devadasan Velmurugan and Ponnusamy Marimuthu. 2017. Antimicrobial Activity of a Novel Secondary Metabolite from Streptomyces sp. and Molecular Docking Studies against Bacterial Leaf Blight Pathogen of Rice.Int.J.Curr.Microbiol.App.Sci. 6(11): 2861-2870. doi: https://doi.org/10.20546/ijcmas.2017.611.337
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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