International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 6, Issue:9, September, 2017

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(9): 3704-3709

A Study on Bacterial Isolates and Their Antibacterial Susceptibility Pattern in Patients with Spontaneous Bacterial Peritonitis in a Tertiary Care Hospital
C. Nithya1*, N. Rathnapriya2 and S. Vasanthi
1Department of Microbiology, Institute of Children, Madras Medical College, Egmore, Chennai, Tamil Nadu, India 2Department of Microbiology, Madras Medical College & RGGGH, Chennai, Tamil Nadu, India
*Corresponding author

Primary peritonitis is otherwise known as Spontaneous Bacterial Peritonitis ((SBP) which is defined as the infection of ascitic fluid without any primary source of infection such as intra-abdominal pathology or perforation of intestine or viscus in the peritoneal cavity. SBP is due to spread of infection from Tran’s mural migration of intestinal organisms into the peritoneal cavity. Spontaneous Bacterial Peritonitis most commonly occurs in cirrhotic patients with ascites due to their poor immune response in ascitic fluid and decreased intestinal motility. The present study was conducted during a one year period (Jan 2013 to Dec 2013). A total of 100 patients with Cirrhotic liver and ascites were included in this study. Gram stain and culture were performed. Antibiotic susceptibility testing was performed by Kirby Bauer disc diffusion method on Mueller Hinton agar. Out of 100 patients, 36 patients were diagnosed as having SBP. There were 24 males and 12 females. In this study, Escherichia coli (54%) was the most common isolated organism followed by Klebsiella pneumoniae (15%). Among the Gram Positive Cocci (GPC), Streptococcus viridans (11%) was the most common isolate followed by Staphylococcus aureus (7%).All isolated GNB were 100% sensitive to Imipenem and among the GPC, all were sensitive to Vancomycin. Appropriate use of selective intestinal decontamination with antibiotics in patients with ascites and also strict follow up of empirical therapy will prevent the severity of SBP.

Keywords: Spontaneous bacterial peritonitis (SBP), Ascitic fluid, Ascitic fluid culture, Gram stain.

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How to cite this article:

Nithya, C., Rathnapriya, N. and Vasanthi, S. 2017. A Study on Bacterial Isolates and Their Antibacterial Susceptibility Pattern in Patients with Spontaneous Bacterial Peritonitis in a Tertiary Care Hospital.Int.J.Curr.Microbiol.App.Sci. 6(9): 3704-3709. doi:
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