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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 6, Issue:9, September, 2017

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(9): 75-80
DOI: https://doi.org/10.20546/ijcmas.2017.609.008


Phenotypic Characterization and Susceptibility Pattern of Gram Negative Bacterial Isolates from Cases of Central Line Associated Blood Stream Infections in a Tertiary Care Institute
Akhilesh, P.S. Tomar1*, Anjali Kushwah2 and Harshada Shah3
1Department of Microbiology, NSCB Medical College, Jabalpur (MP)-482003, India
2Department of Pharmacology, G R Medical College, Gwalior (MP), India
3Department of Microbiology, R D Gardi Medical College, Ujjain (MP), India
*Corresponding author
Abstract:

Resistant and specially Multi Drug Resistant (MDR) Gram negative isolates from the cases of Central Line Associated Blood Stream Infections (CLABSI) are a serious challenge for the treatment to clinicians. Present study was undertaken for phenotypic characterization and susceptibility pattern of Gram negative bacterial isolates from cases of CLABSI in a tertiary care institute. Materials this descriptive cross sectional hospital based study was conducted in a tertiary care teaching hospital over a period of one and half year from January 2012 to June 2013. Centers for Disease Control and Prevention (CDC™s) CLABSI case definitions were used to label a case as CLABSI. Only culture proven cases, out of clinically suspected was included in the study for evaluation. Incidence Central Line Associated Blood Stream Infections were (0.31%) with 38 culture positive cases. The overall rate of CLABSI was 14.64 per 1000 device days with (0.04) device utilization ratio. Gram negative isolates predominated (79%) over Gram positive isolates (21). Among Gram negative bacterial isolates from CLABSI, Klebsiella pneumoniae (40%) was the commonest followed by E. coli (26.66%). %). Rising trends of antimicrobial resistance for common Gram negative bacterial isolates were noticed. Continuous surveillance of CLABSI and microbiological reporting of culture isolates is a need of time in the health care facility.


Keywords: Central Line Associated Blood Stream Infections, Gram negative bacterial infection, Multi Drug Resistant.

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How to cite this article:

Akhilesh, P.S. Tomar, Anjali Kushwah and Harshada Shah. 2017. Phenotypic Characterization and Susceptibility Pattern of Gram Negative Bacterial Isolates from Cases of Central Line Associated Blood Stream Infections in a Tertiary Care Institute.Int.J.Curr.Microbiol.App.Sci. 6(9): 75-80. doi: https://doi.org/10.20546/ijcmas.2017.609.008
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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