National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Burn wounds are one of the most common and devastating forms of trauma. Infections are an important cause of morbidity and mortality in burn patients. It has been estimated that 75% of all deaths following burns are due to infections. To study the bacteriological spectrum of burn wound infections, their antimicrobial sensitivity pattern and time related changes in microbial colonization. The study was conducted in microbiology department and burn care unit in a tertiary care centre. Samples were collected weekly from patients admitted with burn injuries. Relevant patient information was collected in a proforma. Sample processing and antibiotic sensitivity testing was performed according to standard laboratory procedures. A total of 147 microorganisms were isolated from 105 patients with burn wounds admitted in our hospital. The most frequent isolates was Pseudomonas aeruginosa, Staphylococcus aureus, coagulase negative Staphylococcus, Klebsiella pneumoniae, Escherichia coli, Proteus mirabilis and Enterococcus species. Time related changes in burn wound colonization showed an initial predominance of Gram positive cocci in the first week following admission. In the next week, gram negative bacilli began to predominate. Antimicrobial sensitivity testing showed Imipenem and vancomycin, linezolid were most effective against the Gram negative and Gram positive isolates respectively. It is crucial for every burn unit to determine the specific pattern of burn wound colonization, the time related changes in the microbial flora and the antimicrobial resistance pattern. This will enable early treatment of imminent septic episodes with proper empirical systemic antibiotics thus improving overall infection related morbidity and mortality.
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