National Academy of Agricultural Sciences (NAAS)
|
PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Serology is considered the pillar of the syphilis diagnosis. The limitations of traditional serological methods, the advent and availability of new immunochromatographic tests have led to the widespread application of rapid procedures as syphilis screening tools. However, these tests are not widely evaluated. This study was designed to evaluate the performance of a rapid diagnostic test for syphilis known as SD BIOLINE Syphilis 3.0. We carried out a prospective study at the Paraclinical Training and Research Unit in Immunology at the University Hospital Center in Antananarivo from March to May 2016 (3 months). We used SD BIOLINE Syphilis 3.0 to test a sample. Test performance was evaluated using Treponema pallidum Hemagglutination Assay (TPHA) and Rapid Plasma Reagin (RPR) as the reference standard, sensitivity, specificity, positive and negative predictive values were calculated. We have thirty-two reactive samples and eight non-reactive samples. The sensitivity, specificity, and positive and negative predictive values of SD BIOLINE Syphilis 3.0 were 100%. Keeping in view the high sensitivity and specificity of SD BIOLINE Syphilis 3.0 we conclude that the test can be used as a tool for the syphilis rapid diagnosis and as an alternative to TPHA for the detection of antibodies to Treponema pallidum.
Citations |
 |
 |
 |
 |
