Proper cleaning and disinfection of contact lenses is critical to ensuring successful lens wear by eradicating debris and potentially pathogenic microorganisms from the lens surface. In addition, these contemporary Multipurpose Solutions (MPS) have also simplified lens care for patients by incorporating various components that are gentle to ocular tissues and are capable of performing the essential functions of cleaning and disinfecting within a single formulation with protein removal being an added attribute at times in many cases. Low-energy surface acoustic waves can inactivate bacteria and deagglomerate bacterial clusters or flocks.  The present study was therefore, an attempt to determine the effect of low energy surface vibrations on biofilm formation by four different ocular isolates viz. Pseudomonas aeruginosa, Candida albicans, Klebsiella pneumoniae, and Staphylococcus aureus in the presence of three commercially used Multipurpose Solutions namely, Biotrue, Aquasoft and ReNu. The use of low energy surface vibrations along with MPS was found to aid the MPS in their anti-adhesive as well as antimicrobial actions.

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