National Academy of Agricultural Sciences (NAAS)
|
PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Phytopathogenic fungi are major constraints to global crop production, causing substantial losses in yield and quality, while increasing fungicide resistance and environmental concerns challenge conventional disease management. Nanotechnology offers a promising alternative through enhanced surface reactivity, tunable properties, controlled release, and multifunctional antifungal activity. This review summarizes nanotechnology-based approaches for fungal pathogen detection and control, focusing on nanomaterial mechanisms, plant defence modulation, and nano-enabled diagnostics. Nanomaterials can disrupt fungal membrane integrity, redox balance, metabolism, spore germination, and hyphal growth, while also activating plant defence through reactive oxygen species, antioxidant systems, phytohormones, and defence-related genes. Advanced tools, including nanobiosensors, quantum dots, nanopore sequencing, and microneedle platforms, enable rapid pathogen detection. Despite these advantages, concerns regarding ecotoxicity, persistence, beneficial microbiota, cost, standardisation, and regulatory frameworks remain. Future applications require safe-by-design nanomaterials, mechanistic validation, realistic field evaluation, and harmonised regulations for sustainable fungal disease management.
Abkhoo, J., & Panjehkeh, N. (2017). Evaluation of antifungal activity of silver nanoparticles on Fusarium oxysporum. https://doi.org/10.5812/iji.41126
Adisa, I. O., Pullagurala, V. L. R., Peralta Videa, J. R., Dimkpa, C. O., Elmer, W. H., Gardea Torresdey, J. L., & White, J. C. (2017). Recent advances in nano enabled fertilisers and pesticides: A critical review of mechanisms of action. Environmental Science: Nano, 4(8), 1917–1933. https://doi.org/10.1039/c9en00265k
Ahmad, M., Ali, A., Ullah, Z., Sher, H., Dai, D. Q., Ali, M.,... & Ali, I. (2022). Biosynthesized silver nanoparticles using Polygonatum geminiflorum efficiently control fusarium wilt disease of tomato. Frontiers in Bioengineering and Biotechnology, 10, 988607. https://doi.org/10.3389/fbioe.2022.988607
Ameen, F., Alsamhary, K., Alabdullatif, J. A., & ALNadhari, S. (2021). A review on metal-based nanoparticles and their toxicity to beneficial soil bacteria and fungi. Ecotoxicology and Environmental Safety, 213, 112027. https://doi.org/10.1016/j.ecoenv.2021.112027
Cao, X., Wang, C., Luo, X., Yue, L., White, J. C., Elmer, W., Dhankher, O. P., Wang, Z., & Xing, B. (2021). Elemental sulphur nanoparticles enhance disease resistance in tomatoes. ACS Nano, 15(7), 11817–11827. https://doi.org/10.1021/acsnano.1c02917
Clarke, J., Wu, H. C., Jayasinghe, L., Patel, A., Reid, S., & Bayley, H. (2009). Continuous base identification for single molecule nanopore DNA sequencing. Nature Nanotechnology, 4(4), 265–270. https://doi.org/10.1038/nnano.2009.12
Dayou, O., Mwangi, M., Egesa, A. O., Muteti, P. M., & Chumba, C. I. (2018). Application of molecular and biotechnological techniques in plant disease management: A review. African Journal of Biotechnology, 17(31), 938-948. https://doi.org/10.5897/AJB2018.16532
Derbalah, A. S. H., & Elsharkawy, M. M. (2019). A new strategy to control Cucumber mosaic virus using fabricated NiO-nanostructures. Journal of Biotechnology, 306, 134-141. https://doi.org/10.1016/j.jbiotec.2019.10.003
Derbalah, A., Shenashen, M., Hamza, A., Mohamed, A., & El Safty, S. (2018). Antifungal activity of fabricated mesoporous silica nanoparticles against early blight of tomato. Egyptian journal of basic and applied sciences, 5(2), 145-150. https://doi.org/10.1016/j.ejbas.2018.05.002
Dimkpa, C. O., McLean, J. E., Latta, D. E., Manangón, E., Britt, D. W., Johnson, W. P., Boyanov, M. I., & Anderson, A. J. (2013). CuO and ZnO nanoparticles: Phytotoxicity, metal speciation, and induction of oxidative stress in Pseudomonas chlororaphis O6. Chemosphere, 93(6), 1229–1236. https://doi.org/10.1007/s11051-012-1125-9
dos Santos, O. A. L., dos Santos, M. S., Antunes Filho, S., & Backx, B. P. (2024). Nanotechnology for the control of plant pathogens and pests. Plant nano biology, 8, 100080. https://doi.org/10.1016/j.plana.2024.100080
El Abeid, S. E., Abdel Razek, A. F., & Mohamed, A. A. (2024). Green synthesis of CuO nanoparticles and their role in managing tomato Fusarium root rot. Basrah Journal of Agricultural Sciences, 37(1), 89–102. https://doi.org/10.1186/s12951-023-02281-8
El-Shetehy, M., Moradi, A., Maceroni, M., Reinhardt, D., Petri-Fink, A., Rothen-Rutishauser, B.,... & Schwab, F. (2021). Silica nanoparticles enhance disease resistance in Arabidopsis plants. Nature Nanotechnology, 16(3), 344-353. https://doi.org/10.1038/s41565-020-00812-0
Fang, X., Zhang, M., Tang, Q., Wang, Y., & Zhang, X. (2014). Inhibitory effect of Xenorhabdus nematophila TB on plant pathogens Phytophthora capsici and Botrytis cinerea in vitro and in planta. Scientific Reports, 4(1), 4300.
https://doi.org/10.1038/srep04300
Gao, Y., Liang, Y., Dong, H., Niu, J., Tang, J., Yang, J.,... & Cao, Y. (2020). A bioresponsive system based on mesoporous organosilica nanoparticles for smart delivery of fungicide in response to pathogen presence. ACS Sustainable Chemistry & Engineering, 8(14), 5716-5723. https://doi.org/10.1021/acssuschemeng.0c00649
Giannousi, K., Avramidis, I., & Dendrinou Samara, C. (2013). Synthesis, characterisation and evaluation of copper-based nanoparticles as agrochemicals against Phytophthora infestans. RSC Advances, 3(45), 21743–21752. https://doi.org/10.1039/c3ra42118j
Gogoi, R., Dutta, P., & Boruah, R. (2013). Nanosulfur: A new generation fungicide for the management of powdery mildew in black gram. Indian Phytopathology, 66(3), 278–281.
Goodman, J., Mclean, J. E., Britt, D. W., & Anderson, A. J. (2016). Sublethal doses of ZnO nanoparticles remodel production of cell signaling metabolites in the root colonizer Pseudomonas chlororaphis O6. Environmental Science: Nano, 3(5), 1103-1113. https://doi.org/10.1039/c6en00135a
Jamdagni, P., Khatri, P., & Rana, J. S. (2018). Green synthesis of zinc oxide nanoparticles using Ocimum sanctum leaf extract and their antifungal activity. Journal of Environmental Chemical Engineering, 6(5), 6602–6611. https://doi.org/10.1016/j.jksus.2016.10.002
Jung, W. K., Koo, H. C., Kim, K. W., Shin, S., Kim, S. H., & Park, Y. H. (2008). Antibacterial activity and mechanism of action of the silver ion in Staphylococcus aureus and Escherichia coli. Applied and Environmental Microbiology, 74(7), 2171–2178. https://doi.org/10.1128/AEM.02001-07
Kamel, D. A., El Abeid, S. E., & Ahmed, M. A. (2022). Plant mediated synthesis of copper oxide nanoparticles and their role in controlling root rot disease in cucumber. Madras Agricultural Journal, 109(1–3), 45–51. https://doi.org/ 10.1007/978-3-030-05569-1_8
Koul, B., Yakoob, M., & Shah, M. P. (2021). Trends in nanotechnology and its potentialities to control plant pathogenic fungi: A review. Biology, 10(9), 881. https://doi.org/10.3390/biology10090881
Kudjordjie, E. N., Schmidt-Høier, A. S., Brøndum, M. B., Johnsen, M. G., Nicolaisen, M., & Vestergård, M. (2024). Early assessment of fungal and oomycete pathogens in greenhouse irrigation water using Oxford nanopore amplicon sequencing. Plos one, 19(3), e0300381.
https://doi.org/10.1371/journal.pone.0300381
Kulabhusan, P. K., Tripathi, A., & Kant, K. (2022). Gold nanoparticles and plant pathogens: an overview and prospective for biosensing in forestry. Sensors, 22(3), 1259. https://doi.org/10.3390/s22031259
Lakshmeesha, T. R., Murali, M., Ansari, M. A., Udayashankar, A. C., Alzohairy, M. A., Almatroudi, A.,... & Niranjana, S. R. (2020). Biofabrication of zinc oxide nanoparticles from Melia azedarach and its potential in controlling soybean seed-borne phytopathogenic fungi. Saudi Journal of Biological Sciences, 27(8), 1923-1930. https://doi.org/10.1016/j.sjbs.2020.06.013
Lamsal, K., Kim, S. W., Jung, J. H., Kim, Y. S., Kim, K. S., & Lee, Y. S. (2011). Application of silver nanoparticles for the control of Podosphaera pannosa var. rosa causing rose powdery mildew. Plant Pathology Journal, 27(1), 77–82. https://doi.org/10.5941/MYCO.2011.39.3.194
Liu, J., & Lal, R. (2015). Potentials of engineered nanoparticles as fertilisers for increasing agronomic production. Science of the Total Environment, 514, 131–139. https://doi.org/10.1016/j.scitotenv.2015.01.104
Maqbool, Z., Aftab, A., Rizwana, H., Yousaf, Z., & Rehman, S. (2025). Tomato Disease Combat and Yield Optimization Using Selenium Nanoparticles: A Sustainable Nano‐Agriculture Approach. Food Science & Nutrition, 13(7), e70386.
Mikhailov, O. V., & Mikhailova, E. O. (2019). Elemental Silver Nanoparticles: Biosynthesis and Bio Applications. Materials (Basel, Switzerland), 12(19), 3177. https://doi.org/10.3390/ma12193177
Mittler, R., Zandalinas, S. I., Fichman, Y., & Van Breusegem, F. (2022). Reactive oxygen species signalling in plant stress responses. Nature reviews. Molecular cell biology, 23(10), 663–679. https://doi.org/10.1038/s41580-022-00499-2
Moussa, S. H., Tayel, A. A., Alsohim, A. S., & Abdallah, R. R. (2013). Botryticidal activity of nanosized silver‐chitosan composite and its application for the control of gray mold in strawberry. Journal of food science, 78(10), M1589-M1594. https://doi.org/10.1111/1750-3841.12247
Nizamani, M. M., Hughes, A. C., Zhang, H. L., & Wang, Y. (2024). Revolutionizing agriculture with nanotechnology: Innovative approaches in fungal disease management and plant health monitoring. Science of The Total Environment, 928, 172473. https://doi.org/10.1016/j.scitotenv.2024.172473
Ogunyemi, S. O., Zhang, M., Abdallah, Y., Ahmed, T., Qiu, W., Ali, M. A.,... & Li, B. (2020). The bio-synthesis of three metal oxide nanoparticles (ZnO, MnO2, and MgO) and their antibacterial activity against the bacterial leaf blight pathogen. Frontiers in Microbiology, 11, 588326. https://doi.org/10.3389/fmicb.2020.588326
Ogwu, M. C., & Izah, S. C. (2025). Nanotechnology for fungal pathogen control in crops: innovations, public health impacts, and disease prevention. Frontiers in fungal biology, 6, 1653214. https://doi.org/10.3389/ffunb.2025.1653214
Pan, H., Huang, W., Wu, L., Hong, Q., Hu, Z., Wang, M., & Zhang, F. (2022). A pH dual-responsive multifunctional nanoparticle based on mesoporous silica with metal-polymethacrylic acid gatekeeper for improving plant protection and nutrition. Nanomaterials, 12(4), 687. https://doi.org/10.3390/nano12040687
Paul, P. A., Madden, L. V., & Bradley, C. A. (2019). Microneedle based sampling for rapid detection of Phytophthora infestans in potato. Plant Disease, 103(12), 3191–3198. https://doi.org/10.1094/PDIS-04-18-0565-R
Paul, P. A., Madden, L. V., & Bradley, C. A. (2021). Integrated microneedle amplification platform for field diagnosis of late blight. Frontiers in Nanotechnology, 3, 654321. https://doi.org/10.1016/j.bios.2021.113312
Richards, R. M. (1981). Antimicrobial action of silver nitrate. Microbios, 31(124), 83-91.
Riseh, R. S., Hassanisaadi, M., Vatankhah, M., Babaki, S. A., & Barka, E. A. (2022). Chitosan as a potential natural compound to manage plant diseases. International journal of biological macromolecules, 220, 998–1009. https://doi.org/10.1016/j.ijbiomac.2022.08.109
Saharan, V., Sharma, G., Yadav, M., Choudhary, M. K., Sharma, S. S., Pal, A., Raliya, R., & Biswas, P. (2015). Synthesis and in vitro antifungal efficacy of Cu chitosan nanoparticles against pathogenic fungi of tomato. International Journal of Biological Macromolecules, 75, 346–353. https://doi.org/10.1016/j.ijbiomac.2015.01.027
Saqib, S., Zaman, W., Ullah, F., Majeed, I., Ayaz, A., & Hussain Munis, M. F. (2019). Organometallic assembling of chitosan‐Iron oxide nanoparticles with their antifungal evaluation against Rhizopus oryzae. Applied Organometallic Chemistry, 33(11), e5190. https://doi.org/10.1002/aoc.5190
Sardella, D., Gatt, R., & Valdramidis, V. P. (2017). Assessing the efficacy of zinc oxide nanoparticles against Penicillium expansum by automated turbidimetric analysis. Mycology, 9(1), 43–48. https://doi.org/10.1080/21501203.2017.1369187
Sarmah, D., Dhanabalan, S. P., Johnson, I., Sekar, C., Mary, X. A., & Karthikeyan, M. (2025). Diagnostic tools for detection of pathogens and diseases in plantation crops. Journal of microbiological methods, 239, 107294. https://doi.org/10.1016/j.mimet.2025.107294
Sharma, P., Jha, A. B., Dubey, R. S., & Pessarakli, M. (2012). Reactive oxygen species, oxidative damage, and antioxidative defence mechanisms in plants under stressful conditions. Journal of Botany, 2012, 217037. https://doi.org/10.1155/2012/217037
Soares, E. V., & Soares, H. M. (2021). Harmful effects of metal (loid) oxide nanoparticles. Applied Microbiology and Biotechnology, 105(4), 1379-1394. https://doi.org/10.1007/s00253-021-11124-1
Subba, B., Rai, G. B., Bhandary, R., Parajuli, P., Thapa, N., Kandel, D. R., Mulmi, S., Shrestha, S., & Malla, S. (2024). Antifungal activity of zinc oxide nanoparticles (ZnO NPs) on Fusarium equiseti phytopathogen isolated from tomato plant in Nepal. Heliyon, 10(22), e40198. https://doi.org/10.1016/j.heliyon.2024.e40198
Suriyaprabha, R., Karunakaran, G., Yuvakkumar, R., Prabu, P., Rajendran, V., & Kannan, N. (2013, February). Application of silica nanoparticles for increased silica availability in maize. In AIP Conference Proceedings (Vol. 1512, No. 1, pp. 424-425). American Institute of Physics. https://doi.org/10.1063/1.4791092
Sutherland, A. J. (2002). Quantum dots as luminescent probes in biological systems. Current Opinion in Solid State and Materials Science, 6(4), 365-370. https://doi.org/10.1016/S1359-0286(02)00081-5
Tarazona, A., Gómez, J. V., Mateo, E. M., Jiménez, M., & Mateo, F. (2019). Antifungal effect of engineered silver nanoparticles on phytopathogenic and toxigenic Fusarium spp. and their impact on mycotoxin accumulation. International journal of food microbiology, 306, 108259. https://doi.org/10.1016/j.ijfoodmicro.2019.108259
Theologidis, I., Karamitros, T., Vichou, A. E., & Kizis, D. (2023). Nanopore-sequencing metabarcoding for identification of phytopathogenic and endophytic fungi in olive (Olea europaea) twigs. Journal of Fungi, 9(11), 1119. https://doi.org/10.3390/jof9111119
Wang, X., Liu, X., Chen, J., Han, H., & Yuan, Z. (2014). Evaluation and mechanism of antifungal effects of carbon nanomaterials in controlling plant fungal pathogen. Carbon, 68, 798-806. https://doi.org/10.1016/j.carbon.2013.11.072
Wang, X., Zhou, Z., & Chen, F. (2017). Surface Modification of Carbon Nanotubes with an Enhanced Antifungal Activity for the Control of Plant Fungal Pathogen. Materials (Basel, Switzerland), 10(12), 1375. https://doi.org/10.3390/ma10121375
Wang, Y., Deng, C., Shen, Y., Borgatta, J., Dimkpa, C. O., Xing, B., Dhankher, O. P., Wang, Z., White, J. C., & Elmer, W. H. (2022). Surface Coated Sulfur Nanoparticles Suppress Fusarium Disease in Field Grown Tomato: Increased Yield and Nutrient Biofortification. Journal of agricultural and food chemistry, 70(45), 14377–14385. https://doi.org/10.1021/acs.jafc.2c05255
Wang, Y., Sun, Y., Wang, J., Zhou, M., Wang, M., & Feng, J. (2019). Antifungal activity and action mechanism of the natural product cinnamic acid against Sclerotinia sclerotiorum. Plant Disease, 103(5), 944-950. https://doi.org/10.1094/PDIS-08-18-1355-R
Wu, M. C., Lin, T. H., Hsu, K. H., & Hsu, J. F. (2019). Photo-induced disinfection property and photocatalytic activity based on the synergistic catalytic technique of Ag doped TiO2 nanofibers. Applied Surface Science, 484, 326-334. https://doi.org/10.1016/j.apsusc.2019.04.028
Xu, S., Wang, J., Wang, H., Bao, Y., Li, Y., Govindaraju, M.,... & Zhang, M. (2019). Molecular characterization of carbendazim resistance of Fusarium species complex that causes sugarcane pokkah boeng disease. Bmc Genomics, 20(1), 115. https://doi.org/10.1186/s12864-019-5479-6
Yadav, M., Dhamija, A., Sharma, R., Taunk, J., Yashveer, S., & Kumar, S. (2026 b). Biogenic Nanoparticles and Nanobiochar for Rhizosphere Engineering in Salinity-Resilient Agriculture: A Review. https://doi.org/10.9734/jabb/2026/v29i74080
Yadav, M., Dhamija, A., Sharma, R., Verma, M., Taunk, J., & Yashveer, S. (2026 a). Nanotechnology From Soil to Shoot: Nanomaterial Dynamics for Soil Health and Sustainability. In Nanotechnology Applications in Soil Science: From Remediation to Precision Agriculture (pp. 21-50). IGI Global Scientific Publishing. https://doi.org/10.4018/979-8-3693-7006-3.ch002
Zhen, J. B., Kang, P. W., Zhao, M. H., & Yang, K. W. (2019). Silver nanoparticle conjugated star PCL-b-AMPs copolymer as nanocomposite exhibits efficient antibacterial properties. Bioconjugate chemistry, 31(1), 51-63. https://doi.org/10.1021/acs.bioconjchem.9b00739
Citations
|
|
|
