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NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here
ICV 2023: 95.56
Index Copernicus ICI Journals Master List 2023 - IJCMAS--ICV 2023: 95.56
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Original Research Articles Volume : 15, Issue : 6, June, 2026

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com
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Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
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Int.J.Curr.Microbiol.App.Sci.2026.15(6) : 214-221
DOI : https://doi.org/10.20546/ijcmas.2026.1506.023


Effect of Quorum Quenching on Antimicrobial Resistance in Bacteria

Krishna Tandon* and Roonal Kataria
Department of Microbiology, Jai Hind College, Mumbai, India
*Corresponding author
Abstract:

Antimicrobial resistance (AMR) occurs when bacteria evolve to survive drugs designed to kill them. It is an emerging global health crisis driven by the overuse and misuse of antibiotics. This review examines how bacteria develop resistance, form biofilms, and coordinate virulence through quorum sensing (QS), and evaluates quorum quenching (QQ) as a strategy to combat resistant infections. Biofilms protect bacteria by surrounding them with an extracellular matrix that limits antibiotic penetration and helps them evade host immune defense. Through QS, bacteria regulate biofilm formation, virulence, and other collective behaviors by producing and responding to signaling molecules. QQ disrupts these signaling pathways by enzymatically degrading signaling molecules, inhibiting signal synthesis, and antagonizing receptors. By interfering with bacterial communication, QQ weakens biofilms, enhances antibiotic efficacy, and may reduce the development of resistance to antibiotics. Further research is needed to translate QQ-based approaches into effective and sustainable therapies for resistant bacterial infections in vivo.


Keywords: Antimicrobial Resistance, Quorum Sensing, Quorum Quenching, Biofilm

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How to cite this article:

Krishna Tandon and Roonal Kataria. 2026. Effect of Quorum Quenching on Antimicrobial Resistance in Bacteria Int.J.Curr.Microbiol.App.Sci. 15(6): 214-221 doi: https://doi.org/10.20546/ijcmas.2026.1506.023
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