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NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here
ICV 2023: 95.56
Index Copernicus ICI Journals Master List 2023 - IJCMAS--ICV 2023: 95.56
For more details click here
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Original Research Articles Volume : 15, Issue : 5, May, 2026

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
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Editor-in-chief: Dr.M.Prakash
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Int.J.Curr.Microbiol.App.Sci.2026.15(5) : 222-235
DOI : https://doi.org/10.20546/ijcmas.2026.1505.028


Emerging Antibiotic Resistance in Opportunistic Microorganisms: Integrated Surveillance and Next-Generation Therapeutics

S. Arul Jothy1, M. Prakash1, R. Sabarish2, S. Selvasuresh1, K. Arivazhagan3,
S. Saranya4, S. Sivakumar5 and Subasri Prakash6*
1Research Department of Microbiology, Kanchi Shri Krishna College of Arts and Science, Kanchipuram, 631 551, Tamil Nadu, India
2Department of Biotechnology, St.Joseph's College (Arts & Science), Kundrathur Main Road, Kovur, Chennai, 600128, India
3Department of Microbiology, Lakshmi Bangaru Arts and Science College, Pallipettai, Melmaruvathur-603 319, Chengalpet District, Tamil Nadu, India
4PG & Research Department of Zoology, Justice Basheer Ahmed Sayeed College for Women, Teynampet, Chennai-600 018, Tamil Nadu, India
5Department of General Medicine, Meenakshi Medical College Hospital and Research Institute, Enathur, Kanchipuram, Meenakshi Academy of Higher Education & Research (MAHER), Chennai, India
6Undergraduate, Meenakshi Medical College Hospital and Research Institute, Enathur, Kanchipuram. Meenakshi Academy of Higher Education & Research (MAHER), Chennai, India
*Corresponding author
Abstract:

Antimicrobial resistance (AMR) in opportunistic microorganisms is a growing global health concern, especially in hospitalized and immunocompromised persons. These pathogens display a variety of resistance strategies, such as efflux pump activity, target modification, and enzymatic inactivation. Resistance development is accelerated by contributing factors such improper antibiotic use, extended hospital stays, and insufficient infection control. Treatment results are further complicated by the emergence of extensively drug-resistant (XDR), pan-drug-resistant (PDR), and multidrug-resistant (MDR) pathogens worldwide. Early detection has been enhanced by developments in surveillance and quick testing, but there are still few treatment choices. Promising options include CRISPR-based methods, phage treatment, and antimicrobial peptides. To slow the emergence of resistance, it is essential to improve antimicrobial stewardship and infection control procedures.


Keywords: Antimicrobial Resistance (AMR), Multidrug-Resistant Organisms (MDR), Antimicrobial Stewardship, Rapid Diagnostic Surveillance

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How to cite this article:

Arul Jothy S., Prakash M., Selvasuresh S., Arivazhagan K., Saranya S., Sivakumar S. and Subasri Prakash. 2026. Emerging Antibiotic Resistance in Opportunistic Microorganisms: Integrated Surveillance and Next-Generation Therapeutics. Int.J.Curr.Microbiol.App.Sci. 15(5): 222-235 doi: https://doi.org/10.20546/ijcmas.2026.1505.028
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