National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Urinary tract infections (UTIs) remain one of the most prevalent bacterial infections globally, with higher incidence reported among females due to anatomical and physiological predispositions. The increasing emergence of antimicrobial resistance among uropathogens has complicated treatment outcomes and poses a significant public health challenge, particularly in developing regions. This study aimed to characterize bacterial isolates associated with urinary tract infections and evaluate their antimicrobial susceptibility patterns among patients in Sapele, Delta State, Nigeria. A total of 100 midstream urine samples were collected from symptomatic and asymptomatic patients using sterile containers and cultured on cystine lactose electrolyte-deficient (CLED) agar and MacConkey agar using standard microbiological techniques. Bacterial isolates were identified through Gram staining and conventional biochemical tests. Antimicrobial susceptibility testing was performed using the Kirby–Bauer disc diffusion method in accordance with established clinical guidelines. Data were analyzed using descriptive statistics to determine prevalence and resistance patterns. Out of the 100 urine samples analyzed, 46% yielded significant bacterial growth. The prevalence of infection was higher among females (76.09%) compared to males (23.91%), with the highest occurrence observed in women of reproductive age. The predominant isolates were Staphylococcus aureus (45.65%) and Escherichia coli (36.96%), followed by Klebsiella species (13.04%) and Proteus species (4.35%). Antimicrobial susceptibility testing revealed high resistance rates to commonly prescribed antibiotics, particularly Augmentin and Cefuroxime, whereas greater sensitivity was observed with Pefloxacin and Gentamicin. The study confirms the higher burden of urinary tract infections among females and highlights significant antimicrobial resistance among uropathogens in the study population. The findings emphasize the need for routine culture and sensitivity testing prior to antibiotic administration, strengthened antimicrobial stewardship programs, and improved public health education on hygiene practices and rational drug use to mitigate the spread of resistant strains.
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