National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Antimicrobial resistance is defined as the ability of a bacterial strain that is normally susceptible to an antibiotic to acquire partial or complete resistance to it. The objective of this study was to contribute to reducing antimicrobial resistance in pathogenic Enterobacteriaceae strains isolated from stool and urine samples at the AL-SHIFA Clinic in N’Djamena. This descriptive cross-sectional study was conducted on stool and urine samples collected between November 2023 and January 2024. Samples were cultured and subjected to antimicrobial susceptibility testing at the clinic’s laboratory. Of the 137 stool samples and 35 urine samples analyzed, 27 were positive for Enterobacteriaceae—representing 13.87% of stool specimens and 22.86% of urine specimens. A predominance of male patients was observed, with 62.5% in urine samples and 63.16% in stool samples, particularly in the 21–40 and 41–60 age groups. Klebsiella spp. was the most frequent genus, accounting for 33.33% (n=09) of isolates. Resistance levels were recorded as follows: β-lactams 37%, cephalosporins 23%, aminoglycosides 50%, tetracyclines 31%, macrolides 18%, and quinolones 16%. Enterobacteriaceae infections represent a significant public health issue. Appropriate management is essential to prevent the escalation of antibiotic resistance.
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