Follow
International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2023 - IJCMAS--ICV 2023: 95.56 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020] For more details click here

Login as a Reviewer


See Guidelines to Authors
Current Issues
Download Publication Certificate

Original Research Articles                      Volume : 13, Issue:8, August, 2024

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2024.13(8): 195-206
DOI: https://doi.org/10.20546/ijcmas.2024.1308.025


Prevalence and Factors Associated with Serological Detection of Hepatitis B and C in Women of Childbearing Age Received at the Union Hospital in the N’Djamena South Health District in Chad
Naibi Keitoyo Amedé1, 2*, Ngadolo Bongo Nare Richard1, Kakore Syng-Tchouhigbe Arnaud3, Asbagui Faysala Oscar4, Bechir Abdallah Fadoul5, Onmal Justine5, Bainone Pakagne3,Guilia Tampi Babegue6, Onmal Alladoum Carine6 and Et Ban-Bo Bebanto Antipas2, 7
1Laboratory of the Animal Health Division of the Livestock Research Institute for Development (IRED),Route de Farcha, P.O. Box : 433, N’Djamena, Chad
2University of N’Djamena, Doctoral School in Health and Animal Production, Route de Farcha,P.O. Box : 1117, N’Djamena, Chad
3Department of Biomedical, International School of Health Training (EIFS), Avenue Taiwanais,P.O Box : 2448, N’Djamena, Chad
4University of N’Djamena, Doctoral School in Biology and Human Health, Rue de Cherif,P.O. Box: 1117, N’Djamena, Chad
5Laboratory of the UNION Hospital, N’Djamena SouthHealth District, Avenue d’Istabul, N’Djamena, Chad
6Gynecology-obstetrics Department of the Union Hospital, N'Djamena South Health District,Avenue d’Istanbul, N’Djamena, Chad
7Biochemistry Laboratory - Cellular and Molecular Biology - Microbiology (L2BCM) - Faculty of Exact and Applied Sciences (FSEA) - University of N'Djamena P.O. Box : 1117
*Corresponding author
Abstract:

Viral hepatitis is an inflammation of the liver caused by a DNA virus in the case of hepatitis B virus (HBV) and RNA in the case of hepatitis C virus (HCV) and present on all continents. This was a descriptive study with analytical aims carried out from January 2024 to May 2024 in women of childbearing age received at the Union Hospital in the Health District of N'Djamena Sud. The data were collected using a data collection sheet and diagnosis of HBV and HCV was carried out with immunochromatographic tests on the cassettes. Total of 423 patients were enrolled. Among them, 39 samples from patients were positive and 384 negative for HBV giving a prevalence of 9.12% and 3 samples from patients were positive and 420 negative for HCV giving a prevalence of 0.71%. The prevalence of viral hepatitis was 9.83% in women of childbearing age. The age group of 25 to 34 years was the most represented with a frequency of 39.72% followed by that of 20 to 24 years with a rate of 35.22%. In this study, married women were the most represented, with a rate of 58.86% followed by women in cohabitation with a rate of 37.11%. Traders represented 31.91% and housewives a rate of 30.02% in this study. The prevalence was very high in patients with a secondary education level with 39.01% and 23.40% in patients with a primary education level. The factors influencing the circulation of HBV in this study were related to tattooing, multiple partnerships including 33.33% of recorded cases, 27.27% related to a case of HBV in the family; while those influencing the circulation of HCV were related to tattooing (33.33%). This study showed that HBV and HCV still circulate within the population despite systematic HBV vaccination among women attending prenatal consultations.


Keywords: Serological detection, HBV and HCV, childbearing age, Union Hospital


References:

Abbott H C V. 2022. Antibody Detection Test Strip. The BiolineTM HCV, Hepatitis C Virus Antibody (HCV) Test (Whole Blood/Serum/Plasma). N° 7D2342. For In Vitro Diagnostic Use Only. Abbott Diagnostics Medical Co., Ltd. 375 Matsuhidai, Matsudo-shi, Chiba. arcis.techsupport@Abbott.com

All TestTM. 2019. Cassette Test Rapid HBsAg (Whole Blood /Serum/Plasma). N°146035600. Hangzou All Test Biotech Co., Ltd. www.alltests.com.cn

Berthe A. 2021. Carriage of the HBs Antigen in adolescents in the Kadiolo Reference Health Center. Medical thesis. University of Technical Sciences and Technologies of Bamako. (46-62). 132pp.

Global Hepatitis Alliance (GHA). 2024. World Hepatitis Summit 2024. Communication. Content Usage Agreement ABC Global Communications. ADDRESS. 86bis route de Frontenex. Caisse Postale 6364 1211. Geneva 6 Switzerland.

iHAO-WHO. 2023. The elimination of hepatitis can no longer wait. April. Analytical Summary Sheet. 8pp. Consulted on June 22, 2024 on www.aho.afro.who.int.

Mve K V, Wambo Nguessi C, Essiben F et al., (2019). Factors associated with carriage of HBsAg during pregnancy in a highly endemic country. Health Sci. Dis: Vol 20 (5). Available free at www.hsd-fmsb.org

Mvumbi M G. 2022. Prevalence and factors associated with Hepatitis B and C among Sex Workers in Bamako, Mali. Dissertation. Université LAVAL. (55-65). 127pp.

Ndihokubwayo J B. 2022. World Hepatitis Day : bringing hepatitis care closer to beneficiaries. July 28. Communication.

Tchadine D. 2021. Elimination of viral hepatitis B and C in sub-Saharan African populations: barriers, opportunities and challenges. PhD thesis. Aix-Marseille University. (13-15). 111pp.

WHO (2023). World Health Organization. Guidelines on hepatitis B and C testing.

World Health Organization (WHO). 2016. Guidelines on hepatitis B and C testing.

            https://apps.who.int/iris/bitstream/handle/10665/251330/WHO-HIV.23eng.pdf?sequence=1

World Health Organization (WHO). 2024. Elimination of hepatitis B and C worldwide by 2030.

http://apps.who.int/iris/bitstream


Download this article as Download

How to cite this article:

Naibi Keitoyo Amedé, Ngadolo Bongo Nare Richard, Kakore Syng-Tchouhigbe Arnaud, Asbagui Faysala Oscar, Bechir Abdallah Fadoul, Onmal Justine, Bainone Pakagne, Guilia Tampi Babegue, Onmal Alladoum Carine and Et Ban-Bo Bebanto Antipas. 2024. Prevalence and Factors Associated with Serological Detection of Hepatitis B and C in Women of Childbearing Age Received at the Union Hospital in the N’Djamena South Health District in Chad.Int.J.Curr.Microbiol.App.Sci. 13(8): 195-206. doi: https://doi.org/10.20546/ijcmas.2024.1308.025
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

Citations