National Academy of Agricultural Sciences (NAAS)
|
PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The stored herbal raw materials (HRMs) of Justicia adhatoda were found associated with spores of various storage fungi in which Cladosporium cladosporioides exhibited the highest relative density (25.02%) followed by Aspergillus flavus (22.49%) and A. niger (21.46%). The chemical composition of Ocimum tenuiflorum essential oil (OtEO) showed 41 considerable peaks. Eugenol (61.30%) was found as major component followed by β- Caryophyllene (11.89%), Germacrene D (9.14%), α- Cubebene (2.54%) and Carvacrol (2.04%). OtEO showed broad spectrum fungitoxicity and MIC against A. flavus DDUGU-07 was recorded at 0.5 mg/ml while aflatoxin B1 production was completely checked at 0.3 mg/ml. The high performance thin layer chromatography (HPTLC) analysis of fumigated HRMs of J. adhatoda reveals that OtEO was found effective in control the degradation or chemical transformation of medicinal component, vasicine found in J. adhatoda. Hence, OtEO having exclusive merit to possessing antifungal, antiaflatoxigenic and broad fungitoxic spectrum strengthening its safe exploitation as green preservative.
Adams, R. P. (2007). Identification of essential oil components by Gas Chromatography/Mass Spectrometry. Allured Publishing Corporation, Carol Stream, IL.
Ahmed, M., Pickova, J., Ahmad, T., Liaquat, M., Farid, A., and Jahangir, M. (2016). Oxidation of lipids in foods. Sarhad Journal of Agriculture. 32(3): 230-238. https://doi.org/10.17582/journal.sja/2016.32.3.230.238
A?tyn, I., and Twaru?ek, M. (2020). Mycotoxin contamination concerns of herbs and medicinal plants. Toxins. 12: 182.
http://doi.org/10.3390/toxins12030182.
Bajpai, V. K., and Kang, S. C. (2012). In vitro and in vivo inhibition of plant pathogenic fungi by essential oil and extracts of Magnolia liliflora Desr. Journal of Agriculture Science and Technology. 14: 845–856.
Basak, S. (2018). The use of fuzzy logic to determine the concentration betel leaf essential oil and its potency as a juice preservative. Food Chemistry. 240: 1113-1120.
https://doi.org/10.1016/j.foodchem.2017.08.047
Benkerroum, N. (2020). Aflatoxins: producing-molds, structure, health issues and incidence in Southeast Asian and Sub-Saharan African countries. International Journal of Environmental of Research and Public Health. 17: 1215. https://doi.org/10.3390/ijerph17041215.
Bhattacharya, S., Sae-Tia, S., and Fries, B. C. (2020). Candidiasis and mechanisms of antifungal resistance. Antibiotics. 9: 312.
https://doi.org/10.3390/antibiotics9060312.
Chaudhari, A. K., Singh, V. K., Dwivedi, A. K., Das, S., Upadhyay, N., Singh, A., Dkhar, M. S., Kayang, H., Prakash, B., and Dubey, N. K. (2020). Chemically characterised Pimenta dioica (L.) Merr. essential oil as a novel plant based antimicrobial against fungal and aflatoxin B1 contamination of stored maize and its possible mode of action. Natural Product Research. 34(5): 745-749. https://doi.org/10.1080/14786419.2018.1499634
Chellappandian, M., Saravanan, M., Pandikumar, P., Harikrishnan, P., Thirugnanasambantham, K., Subramanian, S., Hairul-Islam, V. I., and Ignacimuthu, S. (2018). Traditionally practiced medicinal plant extracts inhibit the ergosterol biosynthesis of clinically isolated dermatophytic pathogens. Journal of Mycology and Medicine. 28, 143-149.
https://doi.org/10.1016/j.mycmed.2017.11.001.
Chen, L., Guo, W., Zheng, Y., Zhou, J., Liu, T., Chen, W., Liang, D., Zhao, M., Zhu, Y., Wu, Q., and Zhang, J. (2020). Occurrence and characterization of fungi and mycotoxins in contaminated medicinal herbs. Toxins. 12: 30. https://doi.org/10.3390/toxins12010030.
Çorbaci, C. (2020). Biotransformation of terpene and terpenoid derivatives by Aspergillus niger NRRL 326. Biologia. https://doi.org/10.2478/s11756-020-00459-1.
Das, S., Khan, M. L., Rabha, A., and Bhattacharya, D. K. (2009). Ethnomedicinal plants of Manas National Park, Assam, Northeast India. Indian Journal of Traditional Knowledge. 8: 514–517.
Das, S., Singh, V. K., Dwivedi, A. K., Chaudhari, A. K., Upadhyay, N., Singh, P., and Dubey, N. K. (2019). Encapsulation in chitosan-based nanomatrix as an efficient green technology to boost the antimicrobial, antioxidant and in situ efficacy of Coriandrum sativum essential oil. International Journal of Biological Macromolecules, 133, 294-305.
https://doi.org/10.1016/j.ijbiomac.2019.04.070.
Dhankhar, S., Kaur, R., Ruhil, S., Balhara, M., Dhankhar, S., and Chhillar, A. K. (2011). A review on Justicia adhatoda: a potential source of natural medicine. African Journal of Plant Science. 5(11): 620-627.
https://doi.org/10.5897/AJPS.9000004
Didehdar, M., Chegini, Z., and Shariati, A. (2022), Eugenol: A novel therapeutic agent for the inhibition of Candida species infection. Frontiers in Pharmacology, 13: 872127. https://doi.org/10.3389/fphar.2022.872127
Dwivedy, A. K., Singh, V. K., Prakash, B., and Dubey, N. K. (2018). Nanoencapsulated Illicium verum Hook.f. essential oil as an effective novel plant-based preservative against aflatoxin B1 production and free radical generation. Food Chemical Toxicology. 111: 102-113. https://doi.org/10.1016/j.fct.2017.11.007.
Fadel, H. H. M., El-Ghorab, A. H., Hussein, A. M. S., El-Massry, K. F., Lotfy, S. N., Ahmed, M. Y. S., and Soliman, T. N. (2020). Correlation between chemical composition and radical scavenging activity of 10 commercial essential oils: Impact of microencapsulation on functional properties of essential oils. Arabian Journal of Chemistry. 13(8): 6815-6827.
https://doi.org/10.1016/j.arabjc.2020.06.034.
Guo, S., Ma, R., Li, S., Li, Z., Piao, J., and Zhou, R. (2024). Antifungal effects and action mechanism of eugenol on Alternaria panax causing ginseng black spot. Chinese Journal of Pesticide Science. 26(3): 619-624.
https://doi.org/10.16801/j.issn.1008-7303.2024.0026
Hu, Y., Zhang, J., Kong, W., Zhao, G., and Yang, M. (2017). Mechanism of antifungal and anti-aflatoxigenic properties of essential oil derived from turmeric (Curcuma longa L.) on Aspergillus flavus. Food Chemistry. 220:1-8. https://doi.org/10.1016/j.foodchem.2016.09.179.
Iqbal, Z., Akhtar, M., Sabri, M. U., and Altaf, A. (2020) Chemical composition of Ocimum sanctum essential oil by GC-MS analysis. Natural Products Chemistry and Research. 8:6. https://doi.org/10.35248/2329-6836.20.8.388
Josselin, L., De Clerck, C., De Boevre, M., Moretti, A., and Fauconnier, M. L. (2022). Impact of volatile organic compounds on the growth of Aspergillus flavus and related aflatoxin B1 production : A review. International Journal of Molecular Sciences. 23(24): 15557.
https://doi.org/10.3390/ijms232415557
Kedia, A., Prakash, B., Mishra, P. K., Dwivedi, A. K., and Dubey, N. K. (2015). Trachyspermum ammi L. Essential oil as plant based preservative in food system. Industrial Crops and Products. 69: 104-109. https://doi.org/10.1016/j.indcrop.2015.02.013.
Kumar, A., Dubey, N. K., and Srivastava, S. (2013). Antifungal evaluation of Ocimum sanctum essential oil against fungal deterioration of raw materials of Rauvolfia serpentina during storage. Industrial Crops and Products. 45: 30-35. https://doi.org/10.1016/j.indcrop.2012.12.006.
Kumar, A., Shukla, R., Singh, P., and Dubey, N. K. (2009). Biodeterioration of some herbal raw materials by storage fungi and aflatoxin and assessment of Cymbopogon flexuosus essential oil and its components as antifungal. International Biodeterioration and Biodegradation. 63: 712-716.
https://doi.org/10.1016/j.ibiod.2009.03.011.
Kumar, M., Dwivedi, A. K., Sharma, P., Dkhar, M. S., Kayang, H., Raghuwanshi, R., and Dubey, N. K. (2020). Chemically characterised Artemisia nilagirica (Clark) Pamp. essential oil as a safe plant based preservative and shelf-life enhancer of millets against fungal and aflatoxin contamination and lipid peroxidation. Plant Taxonomy and Biosystematics. 154(3): 269-276. https://doi.org/10.1080/11263504.2019.1587539.
Kumar, P., Gupta, A., Mahato, D. K., Pandhi, S., Pandey, A. K., Kargwal, R., Mishra, S., Suhag, R., Sharma, N., Saurabh, V., Paul, V., Kumar, M., Selvakumar, R., Gamlath, S., Kamle, M., Enshasy, H. A., Mokhtar, J. A., and Harakeh, S. (2022). Aflatoxins in cereals and cereal-based products: occurrence, toxicity, impact on human health, and their detoxification and management strategies. Toxins. 14: 687.
https://doi.org/10.3390/toxins14100687
Lasram, S., Zemni, H., Hamdi, Z., Chenenaoui, S., Houissa, H., Tounsi, M. S., and Ghorbel, A. (2019). Antifungal and antiaflatoxigenic activities of Carum carvi L., Coriandrum sativum L. seed essential oils and their major terpene component against Aspergillus flavus. Industrial Crops and Products. 134: 11-18. https://doi.org/10.1016/j.indcrop.2019.03.037.
Marchese, S., Polo, A., Ariano, A., Velotto, S., Costantini, S., and Severino, L. (2018). Aflatoxin B1 and M1 : Biological properties and their involvement in cancer development. Toxins (Basel). 10(6): 214.
https://doi.org/10.3390/toxins10060214
Mishra, P., Prakash, B., Kedia, A., Dwivedy, A. K., Dubey, N. K., and Ahmad, S. (2015). Efficacy of Caesulia axillaris, Cymbopogon khasans and Cymbopogon martini essential oils as plant based preservatives against degradation of raw materials of Andrographis paniculata by fungal spoilage. International Biodeterioration and Biodegradation. 104: 244-250.
https://doi.org/10.1016/j.ibiod.2015.06.015
Newman, D. J., and Cragg, G. M. (2020). Natural Products as a source of new drugs over the nearly four decades from 01/1981 to 09/2019. Journal of Natural Products. 83(3): 770-803. https://doi.org/10.1021/acs.jnatprod.9b01285
Nyarko, A. K., Asare-Anane, H., Ofosuhene, M., and Addy, M. E. (2002). Extract of Ocimum canum lowers blood glucose and facilitates insulin release by isolated pancreatic β-islet cells. Phytomedicine. 9: 346–351.
http://doi.org/10.1078/0944-7113-00124.
Oliveira, R. C., Carvajal-Moreno, M., Correa, B., and Rojo-Callejas, F. (2020). Cellular, physiological and molecular approaches to investigate the antifungal and anti-aflatoxigenic effects of thyme essential oil on Aspergillus flavus. Food Chemestry. 315: 126096.
https://doi.org/10.1016/j.foodchem.2019.126096.
Omotaya, O. P., Omotayo, A. O., Mwanza, M., and Babalola, O. O. (2019). Prevalence of mycotoxins and their consequences on human health. Toxicology Research. 35: 1-7. https://doi.org/10.5487/tr.2019.35.1.001.
Pallares, N., Berrada, H., Font, G., and Ferrer, E. (2022). Mycotoxins occurrence in medicinal herbs dietary supplements and exposure assessment. Journal of Food Science and Technology. 59(7): 2830-2841. https://doi.org/10.1007/s13197-021-05306-y
Pandey, A. K., Kumar, P., Singh, P., Tripathi, N. N., and Bajpai, V. K. (2017). Essential oils: Sources of antimicrobials and food preservatives. Frontiers in Microbiology. 7: 2161.
https://doi.org/10.3389/fmicb.2016.02161.
Pandey, A. K., Singh, P., and Tripathi, N. N. (2014). Chemistry and bioactivities of essential oils of some Ocimum species: an overview. Asian Pacific Journal of Tropical Biomedicine. 4(9): 682-694. https://doi.org/10.12980/APJTB.4.2014C77.
Pavela, R., Benelli, G., Petrelli, R., Cappellacci, L., Lupidi, G., Sut, S., Dall’Acqua, S., and Maggi, F. (2019). Exploring the insecticidal potential of Boldo (Peumus boldus) essential oil toxicity to pests and vectors and non-target impact on the microcrustacean Daphnia magna. Molecules. 24: 879. https://doi.org/10.3390/molecules24050879.
Prakash, B., Singh, P., Mishra, P. K., and Dubey, N. K. (2012). Safety assessment of Zanthoxylum alatum Roxb. essential oil, its antifungal, antiaflatoxin, antioxidant activity and efficacy as antimicrobial in preservation of Piper nigrum L. fruits. International Journal food Microbiology. 153: 183–191.
https://doi.org/10.1016/j.ijfoodmicro.2011.11.007.
Qin, L., Jiang, J. Y., Zhang, L., Dou, X. W., Ouyang, Z., Wan, L., and Yang, M. H. (2020). Occurrence and analysis of mycotoxins in domestic Chinese herbal medicines. Mycology. 11(2): 126-146. https://doi.org/10.1080/21501203.2020.1727578.
Rajkumar, V., Gunasekaran, C., Christy, I.K., Dharmaraj, J., Chinnaraj, P., and Paul, C. A. (2019). Toxicity, antifeedant and biochemical efficacy of Mentha piperita L. essential oil and their major constituents against stored grain pest. Pesticide Biochemistry and Physiology. 156: 138-144. https://doi.org/10.1016/j.pestbp.2019.02.016.
Ravimannan, N., Sevvel, P., and Sarrutharshan, S. (2016). Study on fungi associated with spoilage of bread. International Journal of advanced Research in Biological Sciences. 3(4): 165-167.
Rawat, S., Bhatt, I. D., and Rawal, R. S. (2020). Variation in essential oil composition in rhizomes of natural populations of Hedychium spicatum in different environmental condition and habitats. Journal of Essential Oil Research. 32: 348-360.
https://doi.org/10.1080/10412905.2020.1750497.
Rosengaus, R. B., Lefebvre, M. L., and Traniello, J. F. A. (2000). Inhibition of fungal spore germination by Nasutitermes: evidence for a possible antiseptic role of soldier defensive secretions. Journal of Chemical Ecology. 26: 21–39.
https://doi.org/10.1023/A:1005481209579.
Singh, A., Dwivedy, A. K., Singh, V. K., Upadhyay, N., Chaudhari, A. K., Das, S., and Dubey, N. K. (2019). Essential oils based formulations as safe preservatives for stored plant masticatories against fungal and mycotoxin contamination: A review. Biocatalysis and Agriculural Biotechnology. 17: 313-317.
https://doi.org/10.1016/j.bcab.2018.12.003.
Singh, B. K., Tiwari, S., Maurya, A., Kumar, S., and Dubey, N. K. (2022). Fungal and mycotoxin contamination of herbal raw materials and their protection by nanoencapsulated essential oils: An overview. Biocatalysis and Agricultural Biotechnology. 39:102257.
https://doi.org/10.1016/j.bcab.2021.102257
Srivastava, S., Srivastava, M., Mehrotra, S., and Rawat, A. K. S. (2009). A HPTLC method for chemotaxonomic evaluation of some Curcuma Species and their commercial samples. Journal of Science and Industrial Research. 68: 876–880. https://nopr.niscair.res.in/handle/123456789/6134.
![]() |
![]() |
![]() |
![]() |
![]() |