National Academy of Agricultural Sciences (NAAS)
|
PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Bloodstream infection (BSI) is among the most common acquired illnesses in intensive care unit (ICU) patients and remains one of the most important causes of morbidity and mortality. The current study was aimed to evaluate the incidence of central line?associated bloodstream infections (CLA-BSIs) and bacterial aetiology among the patients admitted at ICU. This study was conducted on randomly selected 1030 patients admitted in the ICU of National Medical College and Teaching Hospital Birgunj, Nepal, from 15thApril 2023to 14th March 2024. The incidence of bloodstream infection and bacteriological profile were done by following standard technique and precautions. This study revealed that the incidence of CLA-BSI was 12.04 per 1000 catheter days. The current study revealed that Gram-negative organisms (66.67%) were the most common organisms associated with the incidence of CLA-BSI in ICU patients which followed by gram-positive organisms (27.08%) and fungal organisms (6.25%). The current study findings also reveal that Salmonella enterica, Escherichia coli, Staphylococcus aureus and Enterococcus spp. were the most common causative agents for CLA-BSI episodes in the ICU patients. It may be prudent to turn our attention to infections caused by these pathogens that may require different approaches to prevention, e.g., optimizing central line maintenance practices.
Al-Yousafi E A, Al-Shamahy H A, Othman A M, AlShawkany A A R M. Bloodstream infections in intensive care unit patients in tertiary hospitals in Sana’a city, Yemen. Universal Journal of Pharmaceutical Research 2023; 8(4):63-69. https://doi.org/10.22270/ujpr.v8i4.977
Centers for Disease Control and Prevention. Bloodstream infection event (central line-associated infection and non-central line-associated bloodstream infection). (2020).
Chaturvedi P, Lamba M, Sharma D, Mamoria V P. Bloodstream infections and antibiotic sensitivity pattern in intensive care unit. Tropical Doctor. 2021; 51(1): 44–48. https://doi.org/10.1177/0049475520977043
Isenberg H D, Clinical Microbiology Procedure Handbook, vol. 1, American Society for Microbiology, Washington, DC, USA, 2nd edition, 2004.
Lee J H, Kim M U, Kim E T, Shim D J, Kim I J, Byeon J H, Kim H B. Prevalence and predictors of peripherally inserted central venous catheter associated bloodstream infections in cancer patients: A multicentre cohort study. Medicine 2020;99:6(e19056). https://doi.org/10.1097/MD.0000000000019056
Malek A M, Abouseif H A, Abd Elaziz K M, Allam M F, Fahim H I. Incidence Of Central Line-associated Bloodstream Infections In Intensive Care Units In A Private Hospital (Cairo, Egypt). The Open Public Health Journal. 2018; 11: 562-571. https://doi.org/10.2174/1874944501811010562
Maqbool S and Sharma R (August 31, 2023) Incidence of Central Line-Associated Bloodstream Infection in a Tertiary Care Hospital in Northern India: A Prospective Study. Cureus 15(8): e44501. https://doi.org/10.7759/cureus.44501
O’Grady N P, Alexander M, Burns L A, Dellinger E P, Garland J, Heard S O, et al., Guidelines for the prevention of intravascular catheter?related infections. Am J Infect Control 2011;39:S1?34. https://doi.org/10.1016/j.ajic.2011.01.003.
Pandey S, Raza S, Bhatta C P. The aetiology of the bloodstream infections in the patients who presented to a tertiary care teaching hospital in Kathmandu, Nepal. Journal of Clinical and Diagnostic Research. 2013;7(4): 638-641. https://doi.org/10.7860/JCDR/2013/4752.2871
Parajuli N P, Acharya S P, Dahal S, Singh J P, Mishra S K, Kattel H P, et al., Epidemiology of device-associated infections in an intensive care unit of a teaching hospital in Nepal: A prospective surveillance study from a developing country. Am J Infect Control. 2017; 45(9):1024-1029. https://doi.org/10.1016/j.ajic.2017.02.040
Parajuli N P, Parajuli H, Pandit R, Shakya J, Khanal P R. Evaluating the Trends of Bloodstream Infections among Pediatric and Adult Patients at a Teaching Hospital of Kathmandu, Nepal: Role of Drug Resistant Pathogens. Canadian Journal of Infectious Diseases and Medical Microbiology. 2017. https://doi.org/10.1155/2017/8763135
Rosenthal V D. International nosocomial infection control consortium (INICC) resources: INICC multidimensional approach and INICC surveillance online system. Am J Infect Control 2016;44:e81?90. https://doi.org/10.1016/j.ajic.2016.01.005
Siefert H, Wisplinghoff H. Bloodstream infection and endocarditis. Topley and Wilson’s Microbiology and Microbial Infections. Vol 1. 10th Ed. London: Edward Arnold; 2005; 509-26.
Singhal T, Shah S, Thakkar P, Naik R. The incidence, aetiology and antimicrobial susceptibility of central line-associated bloodstream infections in intensive care unit patients at a private tertiary care hospital in Mumbai, India. Indian J Med Microbiol 2019;37:521-6. https://doi.org/10.4103/ijmm.IJMM_20_3
Watt B, Miles R S, Collee J G. Tests for identification of bacteria. Practical Medical Microbiology. 14th ed. New York: Churchil Livingstone; 1996;131-50.
Yadav S K, Yadav S P, Bhatta N K, Kanodia P, Singh R R, Khanal B. Risk factors for hospital acquired bloodstream infections in neonatal intensive care unit of B.P. Koirala Institute of Health Sciences, Nepal. Sri Lanka Journal of Child Health. 2017; 46(1): 16-22. https://doi.org/10.4038/sljch.v46i1.8236
Citations |
 |
 |
 |
 |
