Follow
International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2022 - IJCMAS--ICV 2022: 95.28 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020] For more details click here

Login as a Reviewer


See Guidelines to Authors
Current Issues
Download Publication Certificate

Original Research Articles                      Volume : 13, Issue:4, April, 2024

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2024.13(4): 173-183
DOI: https://doi.org/10.20546/ijcmas.2024.1304.020


Diseases Susceptibility with Irritable Bowel Syndrome
Jyoti Rani*, Rimpa Karmakar and Sakshi Saini
School of Allied Health Science, Jaipur National University, Jaipur- 302017, Rajasthan, India
*Corresponding author
Abstract:

IBS is one of the most well-known functional bowel disorders, with more than 10% of the global adult population reporting symptoms consistent with the illness in population-based studies. In standard clinical practice, an IBS diagnosis is obtained based on common symptoms.3 Investigations are frequently limited to a chosen panel of tests that aid in the exclusion of established organic disorders with comparable symptoms, such as inflammatory bowel disease or celiac disease. The actual etiology of IBS is unknown, however anomalies in the gut-brain axis, increased gastrointestinal sensitivity, and dysregulation of gut motility and sensation are thought to have a role. There is evidence that people with IBS are more likely to have fibromyalgia, chronic fatigue syndrome, and depression than the general population. Furthermore, autoimmune illnesses such as rheumatoid arthritis and inflammatory bowel disease are more commonly associated with IBS. The precise processes causing this relationship are unknown, however it is thought that shared genetic, environmental, and neurological variables may contribute to both IBS and other disorders. Understanding this link is critical for effectively managing and treating both IBS and related comorbidities, potentially leading to more complete care plans for affected individuals. Diet has a substantial impact on susceptibility to Irritable Bowel Syndrome (IBS), a common gastrointestinal condition marked by stomach pain, bloating, and changes in bowel movements. Certain dietary components have been identified as triggers for IBS symptoms, which exacerbates the condition in sensitive individuals. Diet does not directly cause IBS, but it can have a substantial impact on illness susceptibility and symptom severity. Adopting a balanced diet high in soluble fiber, probiotics, and nutrient-dense foods while avoiding recognized trigger foods may help to control IBS symptoms and improve overall gastrointestinal health.


Keywords: Irritable Bowel Syndrome, Clinical Review, Diet, Pathology, Health Risks


References:

Almario, C. V., Sharabi, E., Chey, W. D., Lauzon, M., Higgins, C. S., and Spiegel, B. M. (2023). Prevalence and Burden of Illness of Rome IV Irritable Bowel Syndrome in the United States: Results from a Nationwide Cross-Sectional Study. Gastroenterol, 165(6), 1475-1487.

Alnoman, A., Badeghiesh, A. M., Baghlaf, H. A. and Dahan, M. H. (2022). Pregnancy, delivery, and neonatal outcomes among women with irritable bowel syndrome (IBS) an evaluation of over 9 million deliveries. J Matern Fetal Neonatal Med, 35(25), 5935-5942.

Amin, H. S., Irfan, F., Karim, S. I., Almeshari, S. M., Aldosari, K. A., Alzahrani, A. M., and Alsaif, A. A. (2021). The prevalence of irritable bowel syndrome among the Saudi population in Riyadh by use of Rome IV criteria and self-reported dietary restriction. Journal of Gastroenterol. 27(6), 383.

Austin, G. L., Dalton, C. B., Hu, Y., Morris, C. B., Hankins, J., Weinland, S. R., and Drossman, D. A. (2009). A very low-carbohydrate diet improves symptoms and quality of life in diarrhea-predominant irritable bowel syndrome. Clin Gastroenterol Hepatol. 7(6), 706-708.

Berens, S., Banzhaf, P., Baumeister, D., Gauss, A., Eich, W., Schaefert, R., and Tesarz, J. (2020). Relationship between adverse childhood experiences and illness anxiety in irritable bowel syndrome–the impact of gender. J Psychosom Res. 128, 109846.

Bhatt, R. R., Gupta, A., Labus, J. S., Zeltzer, L. K., Tsao, J. C., Shulman, R. J., and Tillisch, K. (2019). Altered brain structure and functional connectivity and its relation to pain perception in girls with irritable bowel syndrome. Psychosom. Med. 81(2), 146.

Bhattarai, Y., Muniz Pedrogo, D. A., and Kashyap, P. C. (2017). Irritable bowel syndrome: a gut microbiota-related disorder? Am J Physiol Gastrointest Liver Physiol. 312(1), G52-G62.

Black, C. J., and Ford, A. C. (2020). Global burden of irritable bowel syndrome: trends, predictions and risk factors. Nat. Rev. Gastroenterol. Hepatol. 17(8), 473-486.

Blomhoff, S., Spetalen, S., Jacobsen, M. B., and Malt, U. F. (2001). Phobic anxiety changes the function of the brain-gut axis in irritable bowel syndrome. Psychosom. Med. 63(6), 959-965.

Böhmer, C. J., and Tuynman, H. A. (2001). The effect of a lactose-restricted diet in patients with a positive lactose tolerance test, earlier diagnosed as irritable bowel syndrome: a 5-year follow-up study. Eur J Gastroenterol Hepatol. 13(8), 941-944.

Camilleri, M. (2009). Genetics and irritable bowel syndrome: from genomics to intermediate phenotype and pharmacogenetics. Dig Dis Sci. 54, 2318-2324.

Camilleri, M. (2020). Irritable Bowel Syndrome: Straightening the road from the Rome criteria. J Neurogastroenterol Motil. 32(11), e13957.

Canavan, C., Card, T., and West, J. (2014). The incidence of other gastroenterological disease following diagnosis of irritable bowel syndrome in the UK: a cohort study. PloS one, 9(9), e106478.

Cancarevic, I., Rehman, M., Iskander, B., Lalani, S., and Malik, B. H. (2020). Is there a correlation between irritable bowel syndrome and lactose intolerance?. Cureus, 12(1).

Chang, L., Kahler, K. H., Sarawate, C., Quimbo, R., and Kralstein, J. (2008). Assessment of potential risk factors associated with ischaemic colitis. J Neurogastroenterol Motil. 20(1), 36-42.

Chey, W. D., Kurlander, J., and Eswaran, S. (2015). Irritable bowel syndrome: a clinical review. Jama, 313(9), 949-958.

Chiaffarino, F., Cipriani, S., Ricci, E., Mauri, P. A., Esposito, G., Barretta, M., and Parazzini, F. (2021). Endometriosis and irritable bowel syndrome: a systematic review and meta-analysis. Arch. Gynecol. Obstet. 303, 17-25.

Chimienti, G., Orlando, A., Lezza, A. M. S., D’Attoma, B., Notarnicola, M., Gigante, I., and Russo, F. (2021). The ketogenic diet reduces the harmful effects of stress on gut mitochondrial biogenesis in a rat model of irritable bowel syndrome. Int J Mol Sci. 22(7), 3498.

Cho, H. S., Park, J. M., Lim, C. H., Cho, Y. K., Lee, I. S., Kim, S. W., and Chung, Y. K. (2011). Anxiety, depression and quality of life in patients with irritable bowel syndrome. Gut and liver, 5(1), 29.

Crowell, M. D. (2004). Role of serotonin in the pathophysiology of irritable bowel syndrome. Br J Pharmacol. 141(8), 1285-1293

Dai, C., Zheng, C. Q., Jiang, M., Ma, X. Y., and Jiang, L. J. (2013). Probiotics and irritable bowel syndrome. World J Gastroenterol. WJG, 19(36), 5973.

Dainese, R., Casellas, F., Marine–Barjoan, E., Vivinus-Nebot, M., Schneider, S. M., Hébuterne, X., and Piche, T. (2014). Perception of lactose intolerance in irritable bowel syndrome patients. Eur J Gastroenterol Hepatol. 26(10), 1167-1175.

Dimidi, E., Rossi, M., and Whelan, K. (2017). Irritable bowel syndrome and diet: where are we in 2018? Curr Opin Clin Nutr Metab Care. 20(6), 456-463.

El-Salhy, M., Hatlebakk, J. G., and Hausken, T. (2019). Diet in irritable bowel syndrome (IBS): interaction with gut microbiota and gut hormones. Nutrients, 11(8), 1824.

El-Salhy, M., Østgaard, H., Gundersen, D., Hatlebakk, J. G., and Hausken, T. (2012). The role of diet in the pathogenesis and management of irritable bowel syndrome. Int J Mol Med. 29(5). 723-731.

Felice, V. D., Quigley, E. M., Sullivan, A. M., O'Keeffe, G. W., and O'Mahony, S. M. (2016). Microbiota-gut-brain signalling in Parkinson's disease: Implications for non-motor symptoms. Parkinsonism & related disorders, 27, 1-8.

Galica, A. N., Galica, R., and Dumitra?cu, D. L. (2022). Diet, fibers, and probiotics for irritable bowel syndrome. J Med Life Sci. 15(2), 174.

Garg, P., Garg, P. K., and Bhattacharya, K. (2023). Psyllium Husk Positively Alters Gut Microbiota, Decreases Inflammation, and Has Bowel-Regulatory Action, Paving the Way for Physiologic Management of Irritable Bowel Syndrome. Gastroenterology.

Ghiasi, F., Amra, B., Sebghatollahi, V., and Azimian, F. (2017). Association of irritable bowel syndrome and sleep apnea in patients referred to sleep laboratory. J Res Med Sc. 22.

Grover, M., Kolla, B. P., Pamarthy, R., Mansukhani, M. P., Breen-Lyles, M., He, J. P., and Merikangas, K. R. (2021). Psychological, physical, and sleep comorbidities and functional impairment in irritable bowel syndrome: Results from a national survey of US adults. PloS one, 16(1), e0245323.

Gupta, D., Ghoshal, U. C., Misra, A., Misra, A., Choudhuri, G., and Singh, K. (2007). Lactose intolerance in patients with irritable bowel syndrome from northern India: A case–control study. J Gastroenterol Hepatol. 22(12), 2261-2265.

Hadjivasilis, A., Tsioutis, C., Michalinos, A., Ntourakis, D., Christodoulou, D. K., and Agouridis, A. P. (2019). New insights into irritable bowel syndrome: from pathophysiology to treatment. J. Gastroenterol. 32(6), 554.

Holtmann, G. J., Ford, A. C., and Talley, N. J. (2016). Pathophysiology of irritable bowel syndrome. The lancet Gastroenterology & hepatology, 1(2), 133-146.

Hustoft, T. N., Hausken, T., Ystad, S. O., Valeur, J., Brokstad, K., Hatlebakk, J. G., and Lied, G. A. (2017). Effects of varying dietary content of fermentable short?chain carbohydrates on symptoms, fecal microenvironment, and cytokine profiles in patients with irritable bowel syndrome. Neurogastroenterology & Motility, 29(4), e12969.

Jamali, R., Jamali, A., Poorrahnama, M., Omidi, A., Jamali, B., Moslemi, N., and Ebrahimi Daryani, N. (2012). Evaluation of health related quality of life in irritable bowel syndrome patients. Health and Quality of Life Outcomes, 10, 1-6.

Khashan, A. S., Quigley, E. M., McNamee, R., McCarthy, F. P., Shanahan, F., and Kenny, L. C. (2012). Increased risk of miscarriage and ectopic pregnancy among women with irritable bowel syndrome. Clin Gastroenterol Hepatol. 10(8), 902-909.

Konings, B., Villatoro, L., Van den Eynde, J., Barahona, G., Burns, R., McKnight, M., and Pasricha, P. J. (2023). Gastrointestinal syndromes preceding a diagnosis of Parkinson’s disease: testing Braak’s hypothesis using a nationwide database for comparison with Alzheimer’s disease and cerebrovascular diseases. Gut, 72(11), 2103-2111.

Labus, J. S., Dinov, I. D., Jiang, Z., Ashe-McNalley, C., Zamanyan, A., Shi, Y., and Mayer, E. A. (2014). Irritable bowel syndrome in female patients is associated with alterations in structural brain networks. Pain®, 155(1), 137-149.

Lee, C., Doo, E., Choi, J. M., Jang, S. H., Ryu, H. S., Lee, J. Y., and Kim, Y. S. (2017). The increased level of depression and anxiety in irritable bowel syndrome patients compared with healthy controls: systematic review and meta-analysis. J Neurogastroenterol Motil. 23(3), 349.

Lewis, J. H. (2010). Alosetron for severe diarrhea-predominant irritable bowel syndrome: safety and efficacy in perspective. Expert Rev of Gastroenterol Hepatol. 4(1), 13-29.

Li, Y., Chen, Y., Jiang, L., Zhang, J., Tong, X., Chen, D., and Le, W. (2021). Intestinal inflammation and Parkinson’s disease. Aging and disease, 12(8), 2052.

Liu, B., Sjölander, A., Pedersen, N. L., Ludvigsson, J. F., Chen, H., Fang, F., and Wirdefeldt, K. (2021). Irritable bowel syndrome and Parkinson’s disease risk: register-based studies. npj Parkinson's Disease, 7(1), 5.

Liu, H., Zou, Y., Kan, Y., Li, X., and Zhang, Y. (2022). Prevalence and Influencing Factors of Irritable Bowel Syndrome in Medical Staff: A Meta-Analysis. Digestive diseases and sciences, 67(11), 5019-5028.

Lomer, M. C., Parkes, G. C., and Sanderson, J. D. (2008). lactose intolerance in clinical practice–myths and realities. Aliment Pharmacol Ther. 27(2), 93-103.

Loo, E. X. L., Wang, D. Y., and Siah, K. T. H. (2020). Association between irritable bowel syndrome and allergic diseases: to make a case for aeroallergen. Int Arch Allergy Immunol. 181(1), 31-42.

Low, E. X., Al Mandhari, M. N., Herndon, C. C., Loo, E. X., Tham, E. H., and Siah, K. T. (2020). Parental, perinatal, and childhood risk factors for development of irritable bowel syndrome: a systematic review. J Neurogastroenterol Motil. 26(4), 437.

Lutgendorff, F., Akkermans, L., and Soderholm, J. D. (2008). The role of microbiota and probiotics in stress-induced gastrointestinal damage. Curr Mol Med. 8(4), 282-298

Maltby, J., Day, L., and Hall, S. (2015). Refining trait resilience: Identifying engineering, ecological, and adaptive facets from extant measures of resilience. PloS one, 10(7), e0131826.

Manning, L. P., Yao, C. K., and Biesiekierski, J. R. (2020). Therapy of IBS: is a low FODMAP diet the answer? Front Psychiatry. 11, 865.

Mazzawi, T., Hausken, T., Gundersen, D., and El-Salhy, M. (2013). Effects of dietary guidance on the symptoms, quality of life and habitual dietary intake of patients with irritable bowel syndrome. Mol Med Rep 8(3), 845-852.

McFarland, L. V., and Dublin, S. (2008). Meta-analysis of probiotics for the treatment of irritable bowel syndrome. World J Gastroenterol. 14(17), 2650.

Midenfjord, I., Polster, A., Sjovall, H., Tornblom, H., and Simren, M. (2019). Anxiety and depression in irritable bowel syndrome: Exploring the interaction with other symptoms and pathophysiology using multivariate analyses. Neurogastroenterol & Motil, 31(8), e13619.

Moayyedi, P., Quigley, E. M., Lacy, B. E., Lembo, A. J., Saito, Y. A., Schiller, L. R., and Ford, A. C. (2014). The effect of fiber supplementation on irritable bowel syndrome: a systematic review and meta-analysis. Official journal of the American College of Gastroenterology| ACG, 109(9), 1367-1374.

Mulak, A., Tache, Y., and Larauche, M. (2014). Sex hormones in the modulation of irritable bowel syndrome. World J Gastroenterol WJG, 20(10), 2433.

Naseri, K., Dabiri, H., Rostami-Nejad, M., Yadegar, A., Houri, H., Olfatifar, M., and Zali, M. R. (2021). Influence of low FODMAP-gluten free diet on gut microbiota alterations and symptom severity in Iranian patients with irritable bowel syndrome. BMC gastroenterology, 21, 1-14.

Nevots, C., Nisior, E., and Sabate, J. M. (2023). Living with Irritable Bowel Syndrome: A significant impact on patients’ everyday lives. Ethics, Medicine and Public Health, 26, 100857.

Nojkov, B., Rubenstein, J. H., Chey, W. D., and Hoogerwerf, W. A. (2010). The impact of rotating shift work on the prevalence of irritable bowel syndrome in nurses. Am. J. Gastroenterol. Suppl. 105(4), 842.

Öhman, L., and Simren, M. (2007). New insights into the pathogenesis and pathophysiology of irritable bowel syndrome. Dig Liver Dis. 39(3), 201-215.

Osadchiy, V., Mayer, E. A., Gao, K., Labus, J. S., Naliboff, B., Tillisch, K., and Gupta, A. (2020). Analysis of brain networks and fecal metabolites reveals brain–gut alterations in premenopausal females with irritable bowel syndrome. Transl Ppsychiatry, 10(1), 367.

Østgaard, H., Hausken, T., Gundersen, D., and El-Salhy, M. (2012). Diet and effects of diet management on quality of life and symptoms in patients with irritable bowel syndrome. Mol Med Rep, 5(6), 1382-1390.

Ozdil, K., Sahin, A., Calhan, T., Kahraman, R., Nigdelioglu, A., Akyuz, U., and Sokmen, H. M. (2011). The frequency of microscopic and focal active colitis in patients with irritable bowel syndrome. BMC gastroenterology, 11, 1-6..

Park, S. H., Naliboff, B. D., Shih, W., Presson, A. P., Videlock, E. J., Ju, T., and Chang, L. (2018). Resilience is decreased in irritable bowel syndrome and associated with symptoms and cortisol response. J Neurogastroenterol Motil, 30(1), e13155.

Patel, A., Hasak, S., Cassell, B., Ciorba, M. A., Vivio, E. E., Kumar, M., and Sayuk, G. S. (2016). Effects of disturbed sleep on gastrointestinal and somatic pain symptoms in irritable bowel syndrome. Aliment Pharmacol Ther. 44(3), 246-258.

QiQiNabi, M. Y., Nauhria, S., Reel, M., Londono, S., Vasireddi, A., Elmiry, M., and Ramdass, P. V. (2022). Endometriosis and irritable bowel syndrome: A systematic review and meta-analyses. Front. Med. 9, 914356.

Reddel, S., Putignani, L., and Del Chierico, F. (2019). The impact of low-FODMAPs, gluten-free, and ketogenic diets on gut microbiota modulation in pathological conditions. Nutrients, 11(2), 373.

Rej, A., Aziz, I., Tornblom, H., Sanders, D. S., and Simren, M. (2019). The role of diet in irritable bowel syndrome: implications for dietary advice. Intern Med J. 286(5), 490-502

Rej, A., Sanders, D. S., Shaw, C. C., Buckle, R., Trott, N., Agrawal, A., and Aziz, I. (2022). Efficacy and acceptability of dietary therapies in non-constipated irritable bowel syndrome: a randomized trial of traditional dietary advice, the low FODMAP diet, and the gluten-free diet. Clin Gastroenterol Hepatol. 20(12), 2876-2887.

Roisinblit, K. C. (2013). Irritable bowel syndrome in women. J Midwifery Womens Health.58(1), 15-24

Roohafza, H., Bidaki, E. Z., Hasanzadeh-Keshteli, A., Daghaghzade, H., Afshar, H., and Adibi, P. (2016). Anxiety, depression and distress among irritable bowel syndrome and their subtypes: an epidemiological population based study. Adv. Biomed. Res. 5.

Self, M. M., Czyzewski, D. I., Chumpitazi, B. P., Weidler, E. M., and Shulman, R. J. (2014). Subtypes of irritable bowel syndrome in children and adolescents. Clin Gastroenterol Hepatol. 12(9), 1468-1473.

Shahdadi, H., Balouchi, A., and Shaykh, A. (2017). Comparison of resilience and psychological wellbeing in women with irritable bowel syndrome and normal women. Materia socio-medica, 29(2), 105.

Si, J. M., Wang, L. J., Chen, S. J., Sun, L. M., and Dai, N. (2004). Irritable bowel syndrome consulters in Zhejiang province: the symptoms pattern, predominant bowel habit subgroups and quality of life. World J Gastroenterol. 10(7), 1059.

Singh, P., Staller, K., Barshop, K., Dai, E., Newman, J., Yoon, S., and Kuo, B. (2015). Patients with irritable bowel syndrome-diarrhea have lower disease-specific quality of life than irritable bowel syndrome-constipation. World J Gastroenterol: WJG, 21(26), 8103.

So, S. Y., and Savidge, T. C. (2021). Sex-bias in irritable bowel syndrome: linking steroids to the gut-brain axis. Front Endocrinol., 12, 684096.

Spiller, R. (2021). Impact of diet on symptoms of irritable bowel syndrome. Nutrients, 13(2), 575.

Suh, D. C., Kahler, K. H., Choi, I. S., Shin, H., Kralstein, J., and Shetzline, M. (2007). Patients with irritable bowel syndrome or constipation have an increased risk for ischaemic colitis. Aliment. Pharmacol. The. 25(6), 681-692.

Talavera, J. I., Parrill, A. M., Elsayad, C., Fogel, J., Riggs, J. C., and Peng, B. (2021). The association between ectopic pregnancy and inflammatory bowel disease, irritable bowel syndrome, and celiac disease: A systematic review. J Obstet Gynaecol Res. 47(5), 1601-1609.

Taub, E., Cuevas, J. L., Cook, E. W., Crowell, M., and Whitehead, W. E. (1995). Irritable bowel syndrome defined by factor analysis gender and race comparisons. Dig Dis Sci 40, 2647-2655.

Ten Berg, M. J., Goettsch, W. G., Van Den Boom, G., Smout, A. J., and Herings, R. M. (2006). Quality of life of patients with irritable bowel syndrome is low compared to others with chronic diseases. Eur J Gastroenterol Hepatol. 18(5), 475-481.

Varjú, P., Gede, N., Szakács, Z., Hegyi, P., Cazacu, I. M., Pecsi, D.and Czimmer, J. (2019). Lactose intolerance but not lactose maldigestion is more frequent in patients with irritable bowel syndrome than in healthy controls: A meta?analysis. J Neurogastroenterol Motil. 31(5), e13527.

Vazquez–Roque, M. I., Camilleri, M., Smyrk, T., Murray, J. A., Marietta, E., ONeill, J., and Zinsmeister, A. R. (2013). A controlled trial of gluten-free diet in patients with irritable bowel syndrome-diarrhea: effects on bowel frequency and intestinal function. Gastroenterol, 144(5), 903-911.

Wang, B., Duan, R., and Duan, L. (2018). Prevalence of sleep disorder in irritable bowel syndrome: a systematic review with meta-analysis. Saudi j gastroenterol. 24(3), 141.

Weaver, K. R., Melkus, G. D. E., and Henderson, W. A. (2017). Irritable bowel syndrome: a review. Am J Nurs, 117(6), 48.

Woodman, C. L., Breen, K., Noyes Jr, R., Moss, C., Fagerholm, R., Yagla, S. J., and Summers, R. (1998). The relationship between irritable bowel syndrome and psychiatric illness: a family study. Psychosom, 39(1), 45-54.

Xiong, L., Wang, Y., Gong, X., and Chen, M. (2017). Prevalence of lactose intolerance in patients with diarrhea-predominant irritable bowel syndrome: data from a tertiary center in southern China. J. health popul. nutr. 36, 1-5.

Yang, J., Fox, M., Cong, Y., Chu, H., Zheng, X., Long, Y., and Dai, N. (2014). Lactose intolerance in irritable bowel syndrome patients with diarrhoea: the roles of anxiety, activation of the innate mucosal immune system and visceral sensitivity.
Aliment. Pharmacol. Ther. 39(3), 302-311.

Yoon, S. Y., Shin, J., Heo, S. J., Chang, J. S., Sunwoo, M. K., and Kim, Y. W. (2022). Irritable bowel syndrome and subsequent risk of Parkinson’s disease: a nationwide population-based matched-cohort study. J. Neurol. 1-9.

Zhang, Y., Feng, L., Wang, X., Fox, M., Luo, L., Du, L.,and Dai, N. (2021). Low fermentable oligosaccharides, disaccharides, monosaccharides, and polyols diet compared with traditional dietary advice for diarrhea-predominant irritable bowel syndrome: a parallel-group, randomized controlled trial with analysis of clinical and microbiological factors associated with patient outcomes. Am J Clin Nutr. 113(6), 1531-1545.


Download this article as Download

How to cite this article:

Jyoti Rani, Rimpa Karmakar and Sakshi Saini. 2024. Diseases Susceptibility with Irritable Bowel Syndrome.Int.J.Curr.Microbiol.App.Sci. 13(4): 173-183. doi: https://doi.org/10.20546/ijcmas.2024.1304.020
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

Citations