National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Tuberculosis remains a major public health problem worldwide. In Sub-Saharan African countries, screening methods and strategies for this disease are weak. This study assesses the prevalence of pulmonary tuberculosis among patients seen at the national public health laboratory in Libreville, Gabon, between January 2020 and December 2022. This is a retrospective observational study conducted from August 1 to October 11, 2023, based on pulmonary tuberculosis diagnostic results obtained between January 2020 and December 2022, in patients presumed to have tuberculosis, at the national public health laboratory in Libreville. Sputum samples from each patient were diagnosed using the MTB/RIF Xpert test. In order to establish correlations between the prevalence of pulmonary tuberculosis and variables such as age, sex, HIV infection and history of tuberculosis, data were entered into an excel 2016 spreadsheet, and exported to R software version 4.0.3, for statistical analysis of trends over time. Within a 95% confidence interval, results were considered significant at p ≤0, 05. In total, data from 2369 patients were collected for the present study. With a sex ratio of 1.21 and a mean age of 51.85 ± 17.45 years, men predominated (n=1296) over women (n=1073). The overall prevalence of pulmonary tuberculosis was reported to be 20.60% (n=488) (95% CI: (0.19- 0.23)) in the present study. In the present study, 29 (5.94%) patients were resistant to rifampicin and 297/1027 (28.92%) patients were co-infected with HIV. Male gender (OR= 2.47, 95% CI 1.19-5.13), age groups between 21 and 40 years (OR= 2.47, 95% CI 1.19-5.13) and between 61 and 80 years (OR= 2.47, 95% CI 1.19-5.13), HIV infection (OR =2.47, 95% CI 1.19-5.13), were significantly associated with the prevalence of pulmonary tuberculosis. The overall prevalence of pulmonary tuberculosis between January 2020 and December 2022 obtained in the present study indicates that this disease persists in Gabon. Effective prevention and control strategies would be appropriate to control this burden.
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