International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
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Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(3): 495-501

Bacteriological profile of neonatal Septicaemia in MIMS, Mandya, India
Mamatha P Samaga* and B. Sumangala
Department of Microbiology, MIMS, Mandya, Karnataka, India
*Corresponding author

Neonatal septicemia (NS) is a clinical syndrome characterized by systemic signs of infection and accompanied by bacteremia in the first month of life. The gold standard for the diagnosis of neonatal septicaemia is the isolation of the bacterial agent from blood culture. The organisms responsible for neonatal sepsis vary across geographical boundaries and with the time of onset of illness. In most developing countries, gram negative bacteria remain the major source of infection. However, in the developed countries, Gram positive organisms have been implicated as the most common causes. In spite of great advances in antimicrobial therapy, neonatal life support measures and the early detection of risk factors, septicaemia continues to be a major cause of mortality and morbidity among neonates around the world. We conducted this study to know the bacterial profile and their antibiogram from clinically suspected neonatal septicaemic cases. This retrospective observational study was conducted in the Dept of Microbiology, MIMS, Mandya after obtaining approval from the Institutional Ethical Committee. The bacterial isolates and their antibiogram from blood samples of clinically suspected neonatal septicaemic cases processed in the Microbiology laboratory during one year (Jan 2014- Dec 2014) were studied from the records of Microbiology laboratory. A total of 128 blood samples from clinically suspected cases of neonatal septicaemia were processed and reported. Among them, 28 (21.9%) samples showed bacterial growth. Among 28 isolates, 15(53.6%) were from Early onset septicaemia and 13(46.4%) were from late onset septicaemia. In Early onset septicaemia, Klebsiella pneumoniae (9, 60%) formed the majority followed by Staphylococcus aureus (3,20%), Citrobacter(2,13.3% ) and Coagulase negative Staphylococcus(1, 6.7% ). In late onset septicaemia, Klebsiella pneumoniae (8,61.5%) was again the predominant isolate followed by Escherichia coli (2, 15.3%), Citrobacter and Staphylococcus aureus and CONS 1(7.4%) each. We  noticed  from this study that Klebsiella was the leading cause of neonatal sepsis and  showed high resistance to commonly used antibiotics like ampicillin and gentamicin. In view of the changing spectrum of the causative agents and their antimicrobial susceptibility patterns, a positive blood culture and the antimicrobial susceptibility testing of the isolates are the best guide in choosing the appropriate antimicrobial therapy in treating neonatal septicaemia.

Keywords:  Neonatal septicemia, Blood culture, Early onset septicaemia, Klebsiella pneumoniae, Late onset septicaemia
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How to cite this article:

Mamatha P Samaga and B. Sumangala. 2016. Bacteriological profile of neonatal Septicaemia in MIMS, Mandya, India.Int.J.Curr.Microbiol.App.Sci. 5(3): 495-501. doi: