National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The main focus of this review article is to need for “an alternative to antibiotic usage in Agriculture and medicine”. Antibiotics, a group of chemicals, either derived from, or naturally produced that along with their synthetic analogues can kill microorganisms at low concentrations. Non-judicious use of these drugs leads to the development of resistance, untreatable and complicated emerging infections demanding search for an alternative. Inspite of new antibiotic and hybrid antibiotic development, natural antibiotics looks to be a promising option. Resistance to antibiotic degradation can lead to the ineffective breakdown of wastes and biomedical wastes because of evolutionary developments. Understanding of the breakdown of antibiotic resistance by use of natural antibiotics when interpreted with metabolic adaptations, biochemical pathways and thermodynamic changes will be of help to understand the problems in medicine and agriculture including development of new microbial species and suggest appropriate measures as the targeted therapeutic intervention in medicine. The work suggests on elucidation and enumeration of the pathways for antibiotic resistance transmission and identification of the prime causes of microbial evolution in environment resulting out from generation of antibiotic resistance. The present work hypothesizes on bioprospecting of natural substances with antimicrobial action to eradicate the problem of antibiotic resistance and suggests the use of natural antibiotics that can change the process of changed metabolic adaptations.
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