National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Dietary phytochemicals are considered as an effective tool to cure various human physiological disorders. Several epidemiological studies have indicated that high intake of natural products is associated with reduced risk of a number of chronic diseases. During recent years consumers have been more concerned about the addition of synthetic additives to food. Therefore, an interest is growing for the search of natural phytoactives with biological activities. Hence, the current study was conducted with the main purpose of phytochemical analysis and determination of antioxidant and antimicrobial activities of Coriandrum sativum (Dhania). Leaves of C. Sativum was subjected to successive solvent extraction by continuous hot extraction (Soxhlet) with double distilled water. Results delineated the major phytochemical present in the aqueous (Aq.) extract of leaves of C. sativum were phenolic compounds/tannins, flavonoids, saponins, alkaloids, proteins and amino acids, glycosides, and reducing sugars. Quantitative estimation of phytochemicals in Aq. extract of leaves of C. sativum revealed that that total polyphenol quantity was found to be highest (7.98 GAE) when compared with total flavonoid quantities (4.23 GAE). The IC50 values exhibited by Aq. extracts of leaves of C. Sativum was found to 3.87 mg/mL. Aq. extracts of leaves of C. sativum exhibited antibacterial activities of against pathogenic organisms viz. Klebsiella pneumonia (11 mm), Staphylococcus pneumonia (15 mm), Proteus mirabilis (12 mm), Eshcherichia coli (10 mm), Salmonella typhi (8 mm), and Enterobacter cloacae (13 mm). Furthermore, the antibacterial activity of Staphylococcus pneumonia was comparable with that of standard Chloramphenicol. In conclusion, this preliminary study confirms that the C. sativum has wide variety of secondary metabolites. Biological activities such as antioxidant and antimicrobial properties of Aq. extract of leaves of C. sativum depicted that C. sativum could be potential drug agent of folk medicines.
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