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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2021.10(8): 578-584
DOI: https://doi.org/10.20546/ijcmas.2021.1008.068


Staphylococcal Positivity and Sensitivity in Invasive Bloodstream Infections using Automated Bactec in Tertiary Care Hospital of North India
Pankaj Katoch1*, Ambika Soodand Surinder Singh2
1Department of Microbiology,
2Department of Paediatrics, IGMC, Shimla, India
*Corresponding author
Abstract:

Staphylococcus aureus is present in the anterior nares of about 20-30% human population. It also resides in the skin, pharynx, acne secretions, and urinary tract also. It can cause a wide spectrum of diseases from fulminant septicemia to localized infections. All the blood culture samples received in the Department of Microbiology for culture by Bactec Bdfx from July 2015 to June2016 were included in the study. The blood culture was observed in the BactecBdfx system for at least 5 days before they are reported as sterile. Among the total 1275 cultures which were positive for bacteria, 344(26.98%) were of Gram-positive bacteria. Among the total of 344 culture isolates positive for Gram-positive bacteria, Staphylococcus aureus was isolated in 184(53.49%) cultures, Among the total 184 cultures, maximum staphylococcal isolates were found in the age group of 19-45 years (26.63%) followed by 0-1 year (24.46%). All the Staphylococcus aureus isolates showed 100% sensitivity to Vancomycin and Linezolid. 90.0% isolates were sensitive to Aztreonam, Ampicillin Sulbactam(86.67%), Amikacin (83.33%), Tobramycin (83.33%), co-trimoxazole(78.80%) and gentamycin (76.08%). S.aureus showed high-level resistance to Penicillin (66.30%), Erythromycin (38.58%), Clindamycin (38.04%), and Ciprofloxacin (30.98%). Staphylococcus aureus was the commonest organism among GPC isolates. S.aureus was the most common isolated organism in the adults and infant group. Staphylococcus aureus was maximum sensitive to Vancomycin and Linezolid while maximum resistant to penicillin.


Keywords: Blood Stream Infections, MRSA, Staphylococcal Positivity, and Sensitivity, Increasing Antibiotic Resistance
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How to cite this article:

Pankaj Katoch, Ambika Sood and Surinder Singh. 2021. Staphylococcal Positivity and Sensitivity in Invasive Bloodstream Infections using Automated Bactec in Tertiary Care Hospital of North India.Int.J.Curr.Microbiol.App.Sci. 10(8): 578-584. doi: https://doi.org/10.20546/ijcmas.2021.1008.068