National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Urinary tract infections are one of the major health problem affecting both sexes of all age group. UTIs are often treated with different broad-spectrum antibiotics. Poor patient compliance and incomplete course of antibiotic therapy have resulted in the evolution of resistance to many of these antibiotics. The aim of this study was to determine the prevalence of bacteria causing urinary tract infections and their susceptibility pattern of patients reporting in MGM Muthoot Medical Centre Pathanamthitta. Mid stream urine (MSU) specimens sent to the laboratory from October 2018 to March 2019 were collected and inoculated onto blood agar and MacConkey agar and incubated at 37ºC for 24 hours. Identification and antibiotic susceptibility test were done following standard operative procedures. 35% (757/2179) samples showed a significant growth out of which 50% (379/757) were females, 31% (234/757) were males and 19% (144/757) were children. Uropathogenic E. coli (UPEC) has been found to be the major pathogen causing UTI in all category of patients which account for 70% (526/757) followed by Klebsiella spp. 19% (140/757), Enterococcus spp. 6% (38), Pseudomonas spp. 4% (32), Proteus spp. 2% (11) and Staphylococcus aureus 1% (9).The higher rate of sensitivity among UPEC isolates were towards imipenem /meropenem (99%), piperacillin – tazobactam (96%), cefaperazone- sulbactam (96%), amikacin (96%) nitrofurantoin (92%) and gentamicin (84 %). The most sensitive oral antibiotics were nitrofurantoin (92%) followed by trimethoprim/sulfamethoxazole ie cotrimoxazole (61%) and the quinolone group (43%). These data may be used to determine trends in antimicrobial susceptibilities, to formulate local antibiotic policies in order to assist clinicians in the rational choice of antibiotic therapy to prevent misuse or overuse of antibiotics.
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