National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692 Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Biofilm is a large collection of colonies containing sessile bacteria which are adhered onto the surface and embedded in the self produced biopolymers such as Extracellular Polymeric Substances (EPS). The surface may be present either in soil or aquatic system as well as in any medical devices or living tissue. These polymeric substances form a cohesive network that interconnects and immobilizes the biofilm cells helping them in mechanical stability. Production of biofilm ultimately helps the bacteria to survive the hostile environment such as different phagocytic cells encountered in living tissue and different harsh conditions like heat, cold, shear forces, desiccation that the inert surface is exposed to. Biofilms are often difficult to treat because of their inherent resistance to both host defens system and antimicrobial agents that ultimately results in persistent infection. Therefore, now a days different nano particles are targeted against biofilms by analyzing and manipulating various atoms using nano technology. This review aims to summerize the current novel solutions to fight against the multi-drug related problems using metal based nanoparticles to target the biofilms.
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