EHV - 1 and 4 both viruses are most important causes of febrile rhinopneumonitis among equine and in some countries EHV - 1 is major factor responsible for abortion and myeloencephalopathy outbreaks. Inhalation of aerosolized viral particles provide major role in disease transmission and virus primarily have an effect on respiratory and uterine mucosa as well as spinal cord causing rhinopneumonitis, abortion and myeloencephalopathy. Previously virus isolation considered as a gold standard for diagnosis but with evolution of advanced molecular approach recently real time PCR is considered as a gold standard. Management of myeloencephalopathic cases is quiet difficult and required long term patience and strong will power. Prevention of these infectious diseases relies heavily on the use of vaccination.

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