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PRINT ISSN : 2319-7692 Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Toxoplasmosis is a zoonosis caused by Toxoplasma gondii, an obligate intracellular parasite. It can cause significant morbidity and mortality in the developing fetus if the pregnant women get acute infection during pregnancy. The aim of the study was to assess the seroprevalence of Toxoplasmosis in antenatal women with bad obstetric history. The seropositivity was analysed according to age, bad obstetric history, socioeconomic and literacy status. A total of 160 antenatal women with BOH and 24 antenatal women with previous normal delivery as control group attending to Govt. General Hospital, Guntur. The serum samples were collected and tested for presence of specific IgM antibodies using a commercial ELISA kit. The seroprevalence of IgM antibodies was 26 (16.25%) in antenatal women with BOH and 0 among the control group. Abortion (53.85%) was the commonest form of BOH followed by still births (19.23%).Various risk factors such as people living in rural areas, low socioeconomic status & illiteracy had greater association of risk of toxoplasmosis than urban population, high socioeconomic status and literacy. This study concluded that there is correlation between toxoplasma infection and Bad obstetric history and abortion is the major cause of fetal loss in pregnant women with bad obstetric history. A previous history of pregnancy wastage & the serological reaction for toxoplasmosis during current pregnancy must be considered while managing BOH cases so as to reduce the adverse outcome.
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