National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692 Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The present study was conducted to evaluate the microfilaricidal efficacy of doxycycline, ivermectin and selamectin in dogs naturally infected with D. repens. A total of eighteen dogs positive for microfilaria by modified Knott's method were included in the study. The species of microfilaria was identified as D. repens based on the morphology and micrometry by modified Knott's and Giemsa’s staining technique. The dogs were divided in to doxycycline, ivermectin and selamectin group with six dogs in each group. The drugs were administered as per standard protocol. The blood samples of dogs from all three groups were analysed for microfilarial count before treatment (0 day), 7th and 14th day of post-treatment. The study demonstrated that, the dogs treated with selamectin showed significant reduction in the microfilarial count from 0 day to 14th day with complete elimination of microfilaria in few dogs followed by ivermectin group which also showed significant reduction in the microfilarial count but, without complete removal of microfilaria in any of the dogs in the group. Even though, decrease in the microfilarial count was observed in dogs treated with doxycycline, they were ineffective in reducing the number of microfilaria significantly.
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