National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Vitex negundo (family: Lamiaceae) is a medicinal shrub which is known to exhibit curative activity against several ailments like relieve catarrh, headache, reduce inflammatory swellings of joints in rheumatic attacks etc. In the present study, the bioactive compounds present in leaf and stem of Vitex negundo were investigated for antimicrobial activity against some pathogenic bacteria (Bacillus subtilis, Staphylococcus aureus, Pseudomonas aeruginosa, and Salmonella typhi) and fungus (Asparagus niger, Cryptococcus neoformans, Saccharomyces cerevisiae, Candida albicans). Dried leaf and stem samples were used to obtain various extracts viz. methanol, ethanol, petroleum ether, hexane and chloroform. The phytochemical analyses showed the presence of phenol, steroids, saponins, coumarin and reducing sugar in the various extracts used in this study. In antibacterial study, leaf hexane extract showed the highest inhibition zone against Pseudomonas aeruginosa while stem ethanolic extract was found to be most effective against Salmonella typhi. The methanol and ethanol leaf extracts were best recorded for the antifungal activity against Cryptococcus neoformans. The stem chloroform extract has also showed maximum inhibition in case of Cryptococcus neoformans growth.
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