National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692 Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Malignant melanoma is malignancy arising from the melanocytes of skin and mucous membrane. Malignant melanoma is most common skin cancer accounting for 78% of skin cancer related deaths. Cho et al., (2005) reported that the risk factors for the melanoma are higher age, male sex, family history of melanoma, higher number of nevi, severe sun burn, light hair color, the data obtained from three large cohort studies. Histopathological classification comprises of 4 subtypes, these are 1. Superficial spreading type, 2. Nodular melanoma, 3. Lentigomaligna melanoma, 4. Acral lentigenous melanoma. Clinical presentation of melanoma depends on location of tumor. Mostly it present as irregular pigmented lesion that grown or changed over time. In our clinical experience we came across different type of melanoma by its site and presentation, which includes melanoma rectum, melanoma sole, melanoma nail bed, melanoma scalp, melanoma foot, melanoma in interdigital area of toes. Melanoma rectum though rare is also entity. Treatment of melanoma varies depending on many factors such as site of presentation, Clark level, and Breslow thickness, having metastasis, and stage of the tumor. Melanoma treatment consists of wide local excision, systemic therapy with ipilimumab, and radiotherapy, intralesional injection of Talimogene, BCG and INF. The clinician should have sound knowledge of various presentations and staging of malignant melanoma and different treatment modalities for each staging. Here we share our experience with malignant.
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