International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 8, Issue:6, June, 2019

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(6): 3321-3337

Quality of Life with Mental Health HIV-Infected Patients in India before and After Antiretroviral Therapy (ART)
Vinay Malik*, A.P. Garg, Tung Virsingh Arya and Maya Datt Joshi
LLRM Medical College and Hospital, Meerut, (UP), India Shobhit Deemed University, Meerut, (UP), India
*Corresponding author

AIDS/HIV is a chronic pandemic disease with significant morbidity and mortality. Although with the advent of HAART an increase in life expectancy and improved QoL has been noticed, evidences regarding prevalence of mental disorders among PLHIV are largely ambiguous. The present study aims to systematically review the evidences about the mental complications in PLHIV before and after HAART therapy. Literature search was conducted for past ten years (i.e. from 2008 to 2019) using the electronic data bases like PubMed, Googlescholar, Google using combination of keywords “AIDS” OR “HIV” AND “quality of life” OR “health related quality of life” AND “neurocognition”, OR “cognitive deficit” OR “psychological complications” OR “mental health” OR “cognitive impairment” OR “depression” OR “anxiety” OR “dementia” AND “randomized controlled trials” OR “randomized clinical trials”, OR “cohort study”, OR “meta-analysis”, OR “systemic review” OR “study”. A total of 27 studies were included in the current systematic review in which 25 were cross sectional studies and 2 were reviews. These 27 studies recorded the neuropsychological variables either as a component of HRQoL/QoL or through usage of specific tools for assessment of depression, anxiety and HAND. Overall based upon the included studies it is evident that the enhanced coexistence of depression, anxiety and HAND with AIDS/HIV is common worldwide. Further, it was observed that the role of HAART in reducing the prevalence of neuropsychological disorders with disease progression is largely meager. It is recommended that baseline assessment of HRQoL, immune markers, and neuropsychological disorders may serve as better treatment strategy with improved outcomes. Further, considering the serious repercussions of mental disorders on HRQoL, it would be beneficial to incorporate additional treatment regimen for them in addition to HAART from the beginning.

Keywords: Mental Health, HIV-Infected patients, Antiretroviral Therapy

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How to cite this article:

Vinay Malik, A.P. Garg, Tung Virsingh Arya and Maya Datt Joshi. 2019. Quality of Life with Mental Health HIV-Infected Patients in India before and After Antiretroviral Therapy (ART).Int.J.Curr.Microbiol.App.Sci. 8(6): 3321-3337. doi:
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.