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PRINT ISSN : 2319-7692 Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The present study was conducted to asses phytochemical and antibacterial activity of various crude extracts viz, pet-ether, chloroform, methanol and aqueous extracts of Salvia aegyptiaca against bacteria and fungi such as Staphylococcus aureus (MTCC Code - 9886), Pseudomonas aeruginosa (MTCC Code - 6458), Aspergillus niger (MTCC Code - 872), Aspergillus flavus (MTCC Code - 8790) by adapting agar well diffusion method. The highest percentage of extraction yield was observed in aqueous extract followed by methanol, chloroform and petether extracts. The phytochemical test revealed that the presence of proteins, carbohydrates, lipids, alkaloids, phenols, flavonoids, steroids, glycosides, tannins, terpenoids and resins. The crude extracts of Salvia aegyptiaca have displayed significant to moderate and dose dependent (25, 50 and 100mg/ml) antibacterial and antifungal activity. The antibacterial activity of methanol extract shows maximum inhibition zone on Gram positive bacteria Staphylococcus aureus compared to Gram negative bacteria Pseudomonas aeruginosa at 100mg/ml concentration. Similarly, the antifungal activity of aqueous extract shows maximum inhibition zone on Aspergillus flavus compared to Aspergillus niger at 100mg/ml concentration. Overall, fungi were more sensitive than the bacterial strains in Salvia aegyptiaca.
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