National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Flowcytometric analysis of T lymphocyte subset viz., CD and CD8 cells in spleen and thymus was done in Nandanam layer chicken of different age groups ranging from day-old to forty weeks. . In spleen, the mean CD4 and CD8 population was found to be the highest at day one and lowest at twenty weeks of age. However, an increase in both the T cell population was detected at forty weeks. Among the two cell types studied, CD8 cells were always higher than the CD4 cells, with significant difference (P<0.05) at day one. The distribution pattern of CD4 and CD8 cells in thymus was slightly different from that of spleen. Thymus had more CD4 cells on day one followed with twelve weeks of age. In contrast, CD8 cells were more on twelve weeks followed with day one. The CD4 and CD8 cell populations were lowest in four weeks of age. A distinct difference was observed in the ratio of CD4 and CD8 cells in the spleen and thymus at different age. At day one the ratio was less in spleen and high in the thymus. However, at eight weeks of age, CD4 cell ratio was high in spleen and low in thymus. Nevertheless, the ratio narrowed down at forty weeks of age.
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