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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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Original Research Articles                      Volume : 8, Issue:4, April, 2019

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(4): 222-228
DOI: https://doi.org/10.20546/ijcmas.2019.804.023


Potential Vaccine Candidates against Nematodes of Veterinary Importance: An Overview
Ekta Singh, Dinesh Chandra, Arvind Prasad and Navneet Kaur*
Division of Parasitology, ICAR-Indian Veterinary Research Institute, Izatnagar-243122, India
*Corresponding author
Abstract:

Nematodes are highly pathogenic and economically important parasites in livestock globally. They strongly challenge the host immunity and in return can be ousted by host via prior anthelmintic treatment. However, this approach is sometimes not appropriate when resistance against anthelmintics develops by these parasites. The problem of parasitism can then be managed by alternative methods where vaccines are thought to play a crucial role. Efforts have been made in past to identify candidate vaccine antigens and are still going on for a wide range of nematode parasite species. The complexities arising due to host-parasite relationship have further challenged scientists to understand mechanisms of vaccine-induced immunity, causing more difficulties in producing effective vaccines though very few vaccines against nematodes have been successfully commercialised. This review highlights some antigens derived from nematode parasites used for the purpose of studying immunoprophylactic responses in livestock.


Keywords: Vaccine, Nematode, immunity, Antigen, Vaccination

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How to cite this article:

Ekta Singh, Dinesh Chandra, Arvind Prasad and Navneet Kaur. 2019. Potential Vaccine Candidates against Nematodes of Veterinary Importance: An Overview.Int.J.Curr.Microbiol.App.Sci. 8(4): 222-228. doi: https://doi.org/10.20546/ijcmas.2019.804.023
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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