National Academy of Agricultural Sciences (NAAS)
|
PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The increase in air pollutants affects both mortality and morbidity of the respiratory system. People are exposed to various indoor allergens like dust mite, pests and pet shedding, manifesting as Asthma. The diagnosis of allergy is either by allergen specific skin test (SPT) or in vitro specific allergen mediated Immunoglobulin E (IgE) measurement. Allergen specific IgE is indicated for evaluating allergy as a more authentic and specific diagnostic tool. But this has not yet been explored much till date. The present study assessed qualitatively the importance of both SPT and allergen specific IgE measurement for diagnosis of allergy. This study was conducted upon bronchial asthma patients. Allergy SPTs were carried out using commercially available antigens. The concentrations of allergen specific IgE antibodies to allergens with most positive skin test reaction were determined using the rapid, solid phase enzyme linked immunosorbent assay. Trends of reaction patterns remained similar in both. Regression analysis studies revealed positive correlation between the tests following some allergens. But corresponding correlation in all forms of allergens could not be established. Therefore characterization and standardization for the commercial allergen and specific IgE assay kit were proposed. In conclusion, specific IgE to aeroallergens seemed a more specific tool for detecting allergen specificity, though SPT seemed to be more sensitive.
Citations |
 |
 |
 |
 |
