International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 5, Issue:12, December, 2016

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(12): 475-485

Incidence of Aerobic Bacterial Infection in Postoperative Closed and Open Fracture Wounds at Tertiary Care Hospital in Western Rajasthan, India
Vinod Maurya1*, Prabhat Kiran Khatri1, R.S. Parihar1, Kishor Raichandani2, Saroj Meena1, Archana Bora1, Laxmi Rathore1, Shivani Khullar1, K.L. Seervi1 and Kamlesh Kumar2
1Department of Microbiology, Dr. S. N. Medical College, Jodhpur, Rajasthan
2Department of Orthopedics, Dr. S. N. Medical College, Jodhpur, Rajasthan
*Corresponding author

Infection is still noted to be one of the major complications in the treatment of fractures. Infections are associated with prolonged hospital stay, leading to higher treatment cost, morbidity and mortality, particularly when the infecting agents are multidrug resistant. To compare incidence of infective agents and their resistance pattern between post-operative closed and open fracture wounds. In this particular study 125 patients of all age group were enrolled with exclusion of patients with history of diabetes mellitus, chronic steroid therapy, chemotherapy and HIV positive patients. Patients were divided into closed fracture and open fracture patients. A total of 120 isolates were obtained from 110 patients. 15 patients were cultured sterile. Organisms obtained were Enterobacter spp. (19.17%), Klebsiella spp. (15.83%), Staphylococcus aureus (12.5%), Coagulase negative Staphylococcus spp. (11.67%), E. coli (10.83%), Pseudomonas (10.83%), Acinetobacter spp. (7.50%), Citrobacter spp. (5.0%), Burkholderia cepacia complex (2.5%), Aeromonas hydrophila (2.5%), Proteus mirabilis (0.83%) and Aerococcus viridans (0.83%). 100% isolates of Staphylococcus species were sensitive against vancomycin, followed by linezolid, gentamicin, tetracycline, ciprofloxacin and azithromycin. Ampicillin, amox-clav and ceftriaxone were most ineffective drugs. Enterobacteriaceae isolates were almost totally resistant against ampicillin followed by amoxy-clav. Levofloxacin and imipenem were found most effective antibiotics. Non-enterobacteriaceae gram negative strains were multidrug resistant, ciprofloxacin, levofloxacin and imipenem were found effective in 50-63% patients. In our study there was no significant difference of antibiotic sensitivity pattern was noted between post-operative closed and open fracture wounds.

Keywords: Post-Operative Infection, Orthopedic Fractures, Closed Fracture, Open Fracture, Antibiotic Sensitivity, Western Rajasthan.

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Vinod Maurya, Prabhat Kiran Khatri, R.S. Parihar, Kishor Raichandani, Saroj Meena, Archana Bora, Laxmi Rathore, Shivani Khullar, K.L. Seervi and Kamlesh Kumar. 2016. Incidence of Aerobic Bacterial Infection in Postoperative Closed and Open Fracture Wounds at Tertiary Care Hospital in Western Rajasthan, India.Int.J.Curr.Microbiol.App.Sci. 5(12): 475-485. doi:
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.