International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 5, Issue:12, December, 2016

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(12): 423-427

Comparison of Performance of ELISA with Indirect Immunofluoresence for the Testing of Antinuclear Antibodies

Euphrasia Latha1, Dhason Therese Mary1, Kavitha Mohanasundaram1,2*and Sankaralingam Rajeswari1  

1Institute of Rheumatology, Madras Medical College, India
2Institute of Rheumatology, Saveetha Medical College Hospital, Thandalam, India
*Corresponding author

Antinuclear antibody testing is one of the major components of immunological investigations. It is very useful in diagnosing autoimmune connective tissue disorders. ELISA, Immunofluoresence and immunoblot are certain investigations by which ANA testing is done. Indian studies about the performance of ANA testing using ELISA and Immunofluoresence are very less and fail to provide concrete evidence. Universally IF has been accepted as gold standard investigation for ANA testing. In India due to cost constraints physicians still use ELISA testing. In this study we aim to look into the performance of ELISA and IF in the testing of ANA testing.

Keywords: ELISA,Immuno-fluoresence and immunoblot.

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How to cite this article:

Euphrasia Latha, J., Dhason Therese Mary, Kavitha Mohanasundaram and Sankaralingam Rajeswari. 2016. Comparison of Performance of ELISA with Indirect Immunofluoresence for the Testing of Antinuclear Antibodies.Int.J.Curr.Microbiol.App.Sci. 5(12): 423-427. doi:
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.