International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 8, Issue:2, February, 2019

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(2): 342-348

A Study of Fungal Septicaemia in New Born at Tertiary Care Hospital
Jitendra Kumar Chaudhary, Amit Kumar Singh*, Shamsheer Ali Teeto and Hariom Sharan
Department of Microbiology, Varunarjun Medical College, Banthra, Shahjahanpur, India
*Corresponding author

Candida species are a common cause of neonatal nosocomial bloodstream infections in infants and are a leading cause of infectious-related mortality in the neonatal intensive care unit (NICU). The objective of this study was to determine the predominant organisms, antifungal sensitivity patterns and clinical risk factors in neonatal fungal blood stream infection cases (BSI) admitted to our hospital. This is a retrospective study of all neonatal fungal BSI cases between May 2018 and October 2018. Fungal sepsis was found in 25/210 (11.9%) of cases. Non Albicans candida (NAC) species were responsible for 85% of cases with Candida glabrata 11 (44%) as the most predominant species. Other species isolated were C. tropicalis 5 (20%), C. albicans 4 (16%), C. paraspinolosis 3 (12%), C. krusei 1 (4%) and C. Kodo 1 (4%). Antifungal sensitivity results showed that most of the NAC isolates especially Candida glabrata, Candida paraspinolosis were resistant to flucanazole, than Candida albicans. Amphotericin B showed more sensitivity than FLK over NAC species. The increase in neonatal fungal BSI and resistant organisms highlights the need to reanalyze use of strict infection control strategies, appropriate preventive and therapeutic measures such as prophylactic antifungal use and a restrictive policy of antibiotic use.

Keywords: Candida, Fungal sepsis, Fungal blood stream infection, Neonates

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How to cite this article:

Jitendra Kumar Chaudhary, Amit Kumar Singh, Shamsheer Ali Teeto and Hariom Sharan. A Study of Fungal Septicaemia in New Born at Tertiary Care Hospital.Int.J.Curr.Microbiol.App.Sci. 8(2): 342-348. doi:
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.