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PRINT ISSN : 2319-7692 Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The present study was undertaken to study the effects of intra-venous (i.v.) ethanol (25%, 50% and 100%) on Electrocardiogram of New Zealand White rabbits. Twelve healthy and clinically normal New Zealand White rabbits of either sex, weighing between 2-3 kg and aged between 1-2 years were selected for the present study. 1 ml of ethanol (25%, 50% and 100%) was injected i.v. in the ear vein of the rabbit and ECG recordings were taken for 50 minutes. Rabbits exhibited a significant decrease in heart rate following the injection of 25% and 50% ethanol and the heart rate remained significantly (P<0.01) depressed for a period of 30 minutes. Low P-wave amplitude was observed. QRS amplitudes have increased significantly in 25% and 50% ethanol treated group. Increased QRS voltage, and prolonged ventricular activation time, likely represents left ventricular hypertrophy. But QRS amplitude has decreased significantly in 100% ethanol treatment. T wave amplitudes significantly increase in 25% and 50% treatment group and decrease in 100% treatment group. QT interval indicating the total duration of electrical activity in the ventricles was significantly increased compared with that of control group (50% treated group).
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