International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2022 - IJCMAS--ICV 2022: 95.28 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020] For more details click here

Login as a Reviewer

See Guidelines to Authors
Current Issues
Download Publication Certificate

Original Research Articles                      Volume : 5, Issue:11, November, 2016

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(11): 499-507

Comparison of the Effects of Simultaneous Use of Methylergonovine and Combined Low-dose (LD) Contraceptive Pills on Hemorrhage Due to Retained Pregnancy Products after Abortion
Maasumeh Kaviani1, Tahere Abdullahi Tehrani2, Sara Azima1*, Khadijeh Abdali1 and Nasrin Asadi3
1Department of Midwifery, School of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran
2Student Research committee, Shiraz University of Medical Sciences, Shiraz, Iran
3Department of Gynaecology and Obstetrics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
*Corresponding author

In some cases, bleeding persists after spontaneous abortion during the first trimester of pregnancy, indicating incomplete expulsion of conception products. The present study aimed to compare the effects of concomitant use of methylergonovine and combined Low Dose (LD) contraceptive pills on prevention of hemorrhage and promotion of complete expulsion of retained pregnancy products. In the present randomized clinical trial, the subjects consisted of 111 women with a complaint of persistent hemorrhage after spontaneous abortion, who had referred to the gynecology clinics of Shiraz University of Medical Sciences. The subjects were randomly divided into 3 groups of 37. Group 1 was required to consume methylergonovine pills for 7 days in conjunction with combined LD contraceptive pills for 21 days, group 2 was given methylergonovine pills alone, and group 3 had to use LD pills alone. The volume of hemorrhage, number of days of hemorrhage and complete expulsion of conception products were evaluated. The data were; however, LD pill resulted in a more significant decrease in the number of days and volume of hemorrhage [P<0.0001]. In addition, in all the three groups, the retained pregnancy products were analyzed using the SPSS statistical software. All the three medication regimens resulted in the expulsion of pregnancy products and a decrease in hemorrhage completely expelled after completion of the course of treatment. In the present study, the combined LD contraceptive pills were more effective in decreasing the number of days hemorrhage persisted and the hemorrhage volume.

Keywords: Spontaneous abortion, Oral Combined Contraceptives, Methergine, Hemorrhage.

Download this article as Download

How to cite this article:

Maasumeh Kaviani, Tahere Abdullahi Tehrani, Sara Azima, Khadijeh Abdali and Nasrin Asadi. 2016. Comparison of the Effects of Simultaneous Use of Methylergonovine and Combined Low-dose (LD) Contraceptive Pills on Hemorrhage Due to Retained Pregnancy Products after Abortion.Int.J.Curr.Microbiol.App.Sci. 5(11): 499-507. doi:
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.