National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Multiple drug resistance is always a challenge to any therapy. Phyto-compounds are one of the major sources of chemical for multiple drug resistance. The compounds used in the present study was extracted from pomegranate fruit peel and purified. Major compound extracted was ellagic acid. The extracted compound was tested for its antibacterial efficacy against wound isolates of Staphylococcus aureus and Methicillin resistant S. aureus (MRSA) using agar well diffusion method. Comparative study was done with gentamicin sulphate. Minimum inhibitory concentration of the ellagic acid was determined by microtube broth dilution method. The results showed that the biological activity of ellagic acid was lesser than gentamicin. Also, the minimum effective dose of ellagic acid was found to be 125μg/ml to MRSA, while the minimum effective doses of gentamicin was 30μg/|ml.
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