This study was conducted to evaluate the effect of probiotic and synbiotic supplementation on production performance of lactating Sahiwal cattle in arid region of Rajasthan. Eighteen apparently healthy Sahiwal cows in their second month of lactation were randomly assigned to three groups. One group acted as control and was given basal diet only and the cows in other two groups were supplemented with probiotic and synbiotic at the dose of 15g/animal/day and 10g/animal/day, for three months. No significant effect of probiotic and synbiotic supplementation was evident on different hematological parameters viz. total leukocyte count of cows and the values of neutrophils, lymphocytes, eosinophils and monocytes were within normal physiological range. The supplementation of probiotic and synbiotic did not have any significant effect on different biochemical parameters serum cholesterol, glucose, calcium and phosphorus levels.

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