International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 7, Issue:10, October, 2018

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(10): 1775-1784

Assessment of Risk Factors in MDR TB Patients. The Reasons behind Their Admission to DOTS plus Centres. Will They Pass Through?
V.P. Amudha1, G. Sucilathangam2*, N. Dilip Jaivanth3 and C. Revathy3
1Department of Microbiology, K.A.P. Viswanatham Government Medical College, Tiruchirappalli - 620001, Tamil Nadu, India
2Department of Microbiology, Government Theni Medical College, Theni - 625512, Tamil Nadu, India
3Department of Microbiology, Tirunelveli Medical College, Tirunelveli - 627 011, Tamil Nadu, India
*Corresponding author

Adherence to MDR-TB treatment remains a pressing public health problem to address. It requires enhanced efforts towards resolving medical problems like adverse drug effects, developing short duration treatment regimens, reducing pill burden, motivational counselling, and flexible timings for DOT services, social support, and family support for patients and improving awareness about disease. Further implementing research is needed for devising strategies to address these issues and to document practices for improvement in adherence to MDR-TB treatment. A questionnaire-based case control study amongst 50 MDR-TB cases and 25 Non-MDR TB controls was conducted. Information was collected from cases and control on a wide range of potential host related, environmental and health service related risk factors for MDR TB. The patients were interviewed using semi constructed questionnaire developed to ascertain potential risk factors. Regarding factors of non-compliance, 22 out of 50 patients were not adhered to treatment due to side effects. 19 out of 30 males, who were alcoholic, were not adhered to treatment. Distance of the health centres from the patients’ home was definitely not a determinant of non-compliance. Socio economic status, occupation, migration, and literacy were also not determinants of non-compliance. Regarding the risk factors of MDR TB, out of 50 cases, 47 cases were previously exposed to TB and this is a major risk factor for developing MDR TB. 19 out of 30 males were smokers and eventually developed MDR TB and this is a major risk factor. Knowledge regarding MDR TB and DOTS Plus was significantly high amongst MDR TB patients. A perception of MDR-TB being more harmful to one’s health was particularly evident among all patients and was willing to alter their lifestyles to complete this course of treatment without interruption.

Keywords: MDR-TB, DOTS, Non-compliance, Risk factors

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How to cite this article:

Amudha, V.P., G. Sucilathangam, N. Dilip Jaivanth and Revathy, C. 2018. Assessment of Risk Factors in MDR TB Patients. The Reasons behind Their Admission to DOTS plus Centres. Will They Pass Through?Int.J.Curr.Microbiol.App.Sci. 7(10): 1775-1784. doi:
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