Dengue fever is increasing in incidence each year and with each monsoon season looms a fear of morbidity and mortality by dengue fever Measures by Government to prevent its spread have not been successful to a very large extent and probably require a more intensive approach towards the etiological causes. Until then early diagnosis and treatment remain the key to escape the damage caused by it. To compare Rapid immunochromatography based kits and ELISA which has been the mainstay of diagnosis of dengue. Serum samples from suspected dengue cases were subjected to both RDT and ELISA for detection of N1S antigen, IgG and IgM antibodies. Out of 285 suspected cases, 65 cases were found to be positive for NS1 by both RDT and ELISA whereas IgM and IgG antibody detection was more by ELISA. Diagnosis of dengue by NS1 antigen by RDT is at par with ELISA whereas antibody detection is better by ELISA.

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