National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The study was conducted in cases of RFM presented within 12 to 24 hours after parturition to Obstetrics Unit of Madras Veterinary College, Chennai. Group I received placebo treatment with one litre of normal saline intravenously. Group II cows, treated with intrauterine proteolytic bolus containing nitrofurazone, metronidazole and urea and antibiotic therapy (Inj. Streptopenicillin @ 20,000 units/kg body weight) without manual removal for 7 days. Groups III cows, received single dose of 2, 00,000 CDU of collagenase plus 40 mg of calcium chloride and 40 mg of sodium bicarbonate dissolved in one litre of normal saline at a pH of 7.5 intravenously through jugular vein (Eiler and Hopkins, 1993). Group IV received single dose of 2,00,000 U of collagenase intravenously. The data on the concentration of serum and lochial NAGase of all the different treatment groups with serum and lochia samples were collected. Further, collected data were compared and analyzed; which showed that the serum NAGase concentration was significantly (P<0.01) higher in group IV on day 0; group II on day 7; group II and IV on day 14; and the overall mean concentration was significantly (P<0.05) lower in groups I and III. The lochial NAGase concentration was significantly (P<0.05) higher in group IV on day 0 and group II on day 7 and 14. These results revealed that the administration of collagenase through intravenous route had achieved better healing and recovery.
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