The present study was conducted to determine the profile of leptin, insulin and estradiol in Bannur female sheep in different age groups maintained under iso-nutritional and iso-managemental conditions at Bandur Breeding Farm, Danagur Village, Malavalli Taluk, Mandya District, Karnataka. A total of 24 randomly selected female sheep as per age were divided in to four groups comprising of six animals in each group. The groups were Group I (>3 to 5 months), Group II (>5 to 7 months), Group III (>7 to 9 months) and Group IV (>9 to 11 months) having uniform body weight in each group. The blood samples collected from jugular vein at 15th, 30th, 45th and 60th day in each group were processed to obtain the serum samples. Leptin, insulin and estradiol in serum levels were estimated by ELISA method. The levels of all the hormones increased as the age advanced and it was proportional to the gain in body weight. It was concluded that the differences in these metabolic hormonal profile during different age of growth could be due to the variation in metabolic activity and level of nutrition. The levels of these hormones could be used as physiological indicators of growth in Bannur female sheep.

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